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RGS13 抗体 (AA 61-90)

This 兔 多克隆 antibody specifically detects RGS13 in WB. It exhibits reactivity toward 人. It has been mentioned in 4+ publications
产品编号 ABIN1881748
发货至: 中国
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Quick Overview for RGS13 抗体 (AA 61-90) (ABIN1881748)

抗原

See all RGS13 抗体
RGS13 (Regulator of G-Protein Signaling 13 (RGS13))

适用

  • 24
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宿主

  • 19
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  • 1

克隆类型

  • 21
  • 3
多克隆

标记

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This RGS13 antibody is un-conjugated

应用范围

  • 21
  • 13
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Western Blotting (WB)

克隆位点

RB40445
  • 抗原表位

    • 6
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    • 3
    • 1
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    • 1
    AA 61-90

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This RGS13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-90 amino acids from the Central region of human RGS13.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Wang, Lippman, Lee, Yang, Khuri, Kim, Lin, Chang, Lotan, Hong, Wu: "Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma." in: Carcinogenesis, Vol. 31, Issue 10, pp. 1755-61, (2010) (PubMed).

    Bansal, DiVietro, Kuehn, Rao, Nocka, Gilfillan, Druey: "RGS13 controls g protein-coupled receptor-evoked responses of human mast cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 11, pp. 7882-90, (2008) (PubMed).

    Han, Huang, Kim, Kehrl: "RGS1 and RGS13 mRNA silencing in a human B lymphoma line enhances responsiveness to chemoattractants and impairs desensitization." in: Journal of leukocyte biology, Vol. 79, Issue 6, pp. 1357-68, (2006) (PubMed).

    Islam, Asplund, Lindvall, Nygren, Liden, Kimby, Christensson, Smith, Sander: "High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma." in: Leukemia, Vol. 17, Issue 9, pp. 1880-90, (2003) (PubMed).

  • 抗原

    RGS13 (Regulator of G-Protein Signaling 13 (RGS13))

    别名

    RGS13

    背景

    The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist.

    分子量

    19135

    NCBI登录号

    NP_002918, NP_658912

    UniProt

    O14921

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling
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