RGS13 抗体 (AA 61-90)
Quick Overview for RGS13 抗体 (AA 61-90) (ABIN1881748)
抗原
See all RGS13 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 61-90
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This RGS13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-90 amino acids from the Central region of human RGS13.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma." in: Carcinogenesis, Vol. 31, Issue 10, pp. 1755-61, (2010) (PubMed).
: "RGS13 controls g protein-coupled receptor-evoked responses of human mast cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 11, pp. 7882-90, (2008) (PubMed).
: "RGS1 and RGS13 mRNA silencing in a human B lymphoma line enhances responsiveness to chemoattractants and impairs desensitization." in: Journal of leukocyte biology, Vol. 79, Issue 6, pp. 1357-68, (2006) (PubMed).
: "High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma." in: Leukemia, Vol. 17, Issue 9, pp. 1880-90, (2003) (PubMed).
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: "Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma." in: Carcinogenesis, Vol. 31, Issue 10, pp. 1755-61, (2010) (PubMed).
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- RGS13 (Regulator of G-Protein Signaling 13 (RGS13))
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别名
- RGS13
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背景
- The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist.
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分子量
- 19135
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NCBI登录号
- NP_002918, NP_658912
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UniProt
- O14921
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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