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CASK 抗体 (AA 589-616)

Cited in 5+ publications. This anti-CASK antibody is a 兔 多克隆 antibody detecting CASK in WB. Suitable for 大鼠.
产品编号 ABIN1881710
发货至: 中国
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Quick Overview for CASK 抗体 (AA 589-616) (ABIN1881710)

抗原

See all CASK 抗体
CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))

适用

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大鼠

宿主

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克隆类型

  • 55
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多克隆

标记

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This CASK antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 589-616

    预测反应

    H, M

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This Rat Cask antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 589-616 amino acids from the Central region of rat Cask.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Tabuchi, Biederer, Butz, Sudhof: "CASK participates in alternative tripartite complexes in which Mint 1 competes for binding with caskin 1, a novel CASK-binding protein." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 22, Issue 11, pp. 4264-73, (2002) (PubMed).

    Chetkovich, Bunn, Kuo, Kawasaki, Kohwi, Bredt: "Postsynaptic targeting of alternative postsynaptic density-95 isoforms by distinct mechanisms." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 22, Issue 15, pp. 6415-25, (2002) (PubMed).

    Hsueh, Wang, Yang, Sheng: "Nuclear translocation and transcription regulation by the membrane-associated guanylate kinase CASK/LIN-2." in: Nature, Vol. 404, Issue 6775, pp. 298-302, (2000) (PubMed).

    Butz, Okamoto, Südhof: "A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain." in: Cell, Vol. 94, Issue 6, pp. 773-82, (1998) (PubMed).

    Hata, Butz, Südhof: "CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 16, Issue 8, pp. 2488-94, (1996) (PubMed).

  • 抗原

    CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))

    别名

    Cask

    背景

    Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TRB1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins, and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1.

    分子量

    103259

    NCBI登录号

    NP_071520

    UniProt

    Q62915

    途径

    Synaptic Vesicle Exocytosis
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