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PRTN3 抗体 (C-Term)

This anti-PRTN3 antibody is a 兔 多克隆 antibody detecting PRTN3 in WB. Suitable for 人. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN1881695
发货至: 中国

Quick Overview for PRTN3 抗体 (C-Term) (ABIN1881695)

抗原

See all PRTN3 抗体
PRTN3 (Proteinase 3 (PRTN3))

适用

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宿主

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克隆类型

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多克隆

标记

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This PRTN3 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB40945
  • 抗原表位

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    AA 228-256, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This PRTN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-256 amino acids from the C-terminal region of human PRTN3.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Kuhl, Korkmaz, Utecht, Kniepert, Schönermarck, Specks, Jenne: "Mapping of conformational epitopes on human proteinase 3, the autoantigen of Wegener's granulomatosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 185, Issue 1, pp. 387-99, (2010) (PubMed).

    Abdgawad, Gunnarsson, Bengtsson, Geborek, Nilsson, Segelmark, Hellmark: "Elevated neutrophil membrane expression of proteinase 3 is dependent upon CD177 expression." in: Clinical and experimental immunology, Vol. 161, Issue 1, pp. 89-97, (2010) (PubMed).

    Hajjar, Broemstrup, Kantari, Witko-Sarsat, Reuter: "Structures of human proteinase 3 and neutrophil elastase--so similar yet so different." in: The FEBS journal, Vol. 277, Issue 10, pp. 2238-54, (2010) (PubMed).

    Källquist, Rosén, Nordenfelt, Calafat, Janssen, Persson, Hansson, Olsson: "Neutrophil elastase and proteinase 3 trafficking routes in myelomonocytic cells." in: Experimental cell research, Vol. 316, Issue 19, pp. 3182-96, (2010) (PubMed).

    Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

  • 抗原

    PRTN3 (Proteinase 3 (PRTN3))

    别名

    PRTN3

    背景

    Polymorphonuclear leukocyte serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema when administered by tracheal insufflation to hamsters.

    分子量

    27807

    NCBI登录号

    NP_002768

    UniProt

    P24158
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