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PPM1F 抗体 (AA 275-303)

Name: PPM1F 抗体 (AA 275-303)
SKU: ABIN1881678
Availability: OutOfStock

This anti-PPM1F antibody is a 兔多克隆 antibody detecting PPM1F in WB. Suitable for 人. This Primary Antibody has been cited in 4+ publications.

M1F Antibody (Center) (ABIN1881678 and ABIN2838899) western blot analysis in MCF-7 cell line lysates (35 μg/lane). (PPM1F 抗体 (AA 275-303))

1 image

(4 references)

产品编号 ABIN1881678

发货至: 中国

Quick Overview for PPM1F 抗体 (AA 275-303) (ABIN1881678)

抗原

See all PPM1F 抗体

PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))

适用

人

宿主

兔

克隆类型

多克隆

标记

This PPM1F antibody is un-conjugated

应用范围

Western Blotting (WB)

克隆位点

RB41919

Discover our top product PPM1F Primary Antibody

抗原表位
11

8

7

6

3

3

3

2

1

1

1

1
AA 275-303

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This PPM1F antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-303 amino acids from the Central region of human PPM1F.

亚型

Ig Fraction
anti-Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F) (AA 1-76) antibody
PPM1F 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F) (AA 1-100) antibody
PPM1F 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A9 unconjugated

anti-Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F) (AA 1-100) antibody
PPM1F 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1G10 unconjugated

anti-Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F) (AA 1-454) antibody
PPM1F 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated

anti-Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F) (AA 1-100) antibody
PPM1F 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

anti-Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F) (AA 1-454) antibody
PPM1F 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F) (AA 11-40), (N-Term) antibody
PPM1F 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB5923 unconjugated

anti-Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F) (AA 1-190) antibody
PPM1F 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F) (AA 275-303) antibody (HRP)
PPM1F 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal HRP

anti-Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F) (AA 275-303) antibody (PE)
PPM1F 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal PE

应用备注

WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Harvey, Banga, Ozer: "Regulation of the multifunctional Ca2+/calmodulin-dependent protein kinase II by the PP2C phosphatase PPM1F in fibroblasts." in: The Journal of biological chemistry, Vol. 279, Issue 23, pp. 24889-98, (2004) (PubMed).

Koh, Tan, Manser, Lim: "The p21-activated kinase PAK is negatively regulated by POPX1 and POPX2, a pair of serine/threonine phosphatases of the PP2C family." in: Current biology : CB, Vol. 12, Issue 4, pp. 317-21, (2002) (PubMed).

Tan, Chan, Tan, Yu: "The Caenorhabditis elegans sex-determining protein FEM-2 and its human homologue, hFEM-2, are Ca2+/calmodulin-dependent protein kinase phosphatases that promote apoptosis." in: The Journal of biological chemistry, Vol. 276, Issue 47, pp. 44193-202, (2001) (PubMed).

Kitani, Ishida, Okuno, Takeuchi, Kameshita, Fujisawa: "Molecular cloning of Ca2+/calmodulin-dependent protein kinase phosphatase." in: Journal of biochemistry, Vol. 125, Issue 6, pp. 1022-8, (1999) (PubMed).
抗原

PPM1F (Protein Phosphatase 1F (PP2C Domain Containing) (PPM1F))

别名

PPM1F

背景

The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined.

分子量

49831

NCBI登录号

NP_055449

UniProt

P49593

途径

Positive Regulation of Endopeptidase Activity