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Progesterone Receptor 抗体 (AA 523-550)

This anti-Progesterone Receptor antibody is a 兔 多克隆 antibody detecting Progesterone Receptor in WB. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN1881649
发货至: 中国

Quick Overview for Progesterone Receptor 抗体 (AA 523-550) (ABIN1881649)

抗原

See all Progesterone Receptor (PGR) 抗体
Progesterone Receptor (PGR)

适用

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宿主

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克隆类型

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多克隆

标记

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This Progesterone Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB41474
  • 抗原表位

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    AA 523-550

    预测反应

    M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This PGR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 523-550 amino acids from the Central region of human PGR.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Van Belle, Van Calster, Brouckaert, Vanden Bempt, Pintens, Harvey, Murray, Naume, Wiedswang, Paridaens, Moerman, Amant, Leunen, Smeets, Drijkoningen, Wildiers, Christiaens, Vergote, Van Huffel, Neven: "Qualitative assessment of the progesterone receptor and HER2 improves the Nottingham Prognostic Index up to 5 years after breast cancer diagnosis." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 28, Issue 27, pp. 4129-34, (2010) (PubMed).

    Geradts, Bean, Bentley, Barry: "The oncotype DX recurrence score is correlated with a composite index including routinely reported pathobiologic features." in: Cancer investigation, Vol. 28, Issue 9, pp. 969-77, (2010) (PubMed).

    Tang, Wang, Hicks, Wang, Schiffhauer, McMahon, Yang, Shayne, Huston, Skinner, Griggs, Lyman: "A lower Allred score for progesterone receptor is strongly associated with a higher recurrence score of 21-gene assay in breast cancer." in: Cancer investigation, Vol. 28, Issue 9, pp. 978-82, (2010) (PubMed).

  • 抗原

    Progesterone Receptor (PGR)

    别名

    PGR

    背景

    This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap. The location of transcription initiation for isoform A has not been clearly determined.

    分子量

    98981

    NCBI登录号

    NP_000917, NP_001189403, NP_001258091

    UniProt

    P06401

    途径

    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
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