PDE8B 抗体 (AA 296-324)
This anti-PDE8B antibody is a 兔 多克隆 antibody detecting PDE8B in WB. Suitable for 小鼠. This Primary Antibody has been cited in 3+ publications.
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(3 references)Quick Overview for PDE8B 抗体 (AA 296-324) (ABIN1881646)
抗原
See all PDE8B 抗体
PDE8B
(phosphodiesterase 8B (PDE8B))
适用
小鼠
宿主
兔
克隆类型
多克隆
标记
This PDE8B antibody is un-conjugated
应用范围
Western Blotting (WB)
克隆位点
RB42219
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抗原表位
- AA 296-324
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This PDE8B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-324 amino acids from the Central region of human PDE8B.
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亚型
- Ig Fraction
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anti-phosphodiesterase 8B (PDE8B) (Internal Region) antibody
PDE8B 适用: 人, 马, 猴, Bat IHC (p), IHC 宿主: 兔 Polyclonal unconjugated
anti-phosphodiesterase 8B (PDE8B) (AA 18-110) antibodyPDE8B 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Haplotype analysis of the promoter region of phosphodiesterase type 8B (PDE8B) in correlation with inactivating PDE8B mutation and the serum thyroid-stimulating hormone levels." in: Thyroid : official journal of the American Thyroid Association, Vol. 20, Issue 4, pp. 363-7, (2010) (PubMed).
: "Phosphodiesterase 8B gene polymorphism is associated with subclinical hypothyroidism in pregnancy." in: The Journal of clinical endocrinology and metabolism, Vol. 94, Issue 11, pp. 4608-12, (2009) (PubMed).
: "Abnormalities of cAMP signaling are present in adrenocortical lesions associated with ACTH-independent Cushing syndrome despite the absence of mutations in known genes." in: European journal of endocrinology / European Federation of Endocrine Societies, Vol. 161, Issue 1, pp. 153-61, (2009) (PubMed).
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: "Haplotype analysis of the promoter region of phosphodiesterase type 8B (PDE8B) in correlation with inactivating PDE8B mutation and the serum thyroid-stimulating hormone levels." in: Thyroid : official journal of the American Thyroid Association, Vol. 20, Issue 4, pp. 363-7, (2010) (PubMed).
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- PDE8B (phosphodiesterase 8B (PDE8B))
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别名
- PDE8B
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背景
- The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.
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分子量
- 98979
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NCBI登录号
- NP_001025022, NP_001025023, NP_001025024, NP_001025025, NP_003710
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UniProt
- O95263
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途径
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process
抗原
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