OTX2 抗体 (C-Term)
(5 references)Quick Overview for OTX2 抗体 (C-Term) (ABIN1881611)
抗原
See all OTX2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 261-289, C-Term
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预测反应
- X, Zf, M
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This OTX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-289 amino acids from the C-terminal region of human OTX2.
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亚型
- Ig Fraction
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anti-Orthodenticle Homeobox 2 (OTX2) antibody
OTX2 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 1H12C4B5 unconjugated
anti-Orthodenticle Homeobox 2 (OTX2) (N-Term) antibodyOTX2 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬, 绵羊, 兔, 马, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Orthodenticle Homeobox 2 (OTX2) antibodyOTX2 适用: 大鼠, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Orthodenticle Homeobox 2 (OTX2) (AA 1-297) antibodyOTX2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Orthodenticle Homeobox 2 (OTX2) (AA 86-135) antibodyOTX2 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬, 绵羊, 兔, 马, Cow, 豚鼠, Bat, Hamster, Pig, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Orthodenticle Homeobox 2 (OTX2) (AA 140-280) antibodyOTX2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Orthodenticle Homeobox 2 (OTX2) antibodyOTX2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Orthodenticle Homeobox 2 (OTX2) (AA 261-289) antibodyOTX2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Orthodenticle Homeobox 2 (OTX2) (C-Term) antibodyOTX2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Orthodenticle Homeobox 2 (OTX2) (AA 102-135) antibodyOTX2 适用: 人 WB 宿主: 兔 Polyclonal RB50908 unconjugated
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应用备注
- WB: 1:1000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "SOX9, through interaction with microphthalmia-associated transcription factor (MITF) and OTX2, regulates BEST1 expression in the retinal pigment epithelium." in: The Journal of biological chemistry, Vol. 285, Issue 35, pp. 26933-44, (2010) (PubMed).
: "The transcription factor orthodenticle homeobox 2 influences axonal projections and vulnerability of midbrain dopaminergic neurons." in: Brain : a journal of neurology, Vol. 133, Issue Pt 7, pp. 2022-31, (2010) (PubMed).
: "A novel loss-of-function mutation in OTX2 in a patient with anophthalmia and isolated growth hormone deficiency." in: Human genetics, Vol. 127, Issue 6, pp. 721-9, (2010) (PubMed).
: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).
: "Mutational screening of CHX10, GDF6, OTX2, RAX and SOX2 genes in 50 unrelated microphthalmia-anophthalmia-coloboma (MAC) spectrum cases." in: The British journal of ophthalmology, Vol. 94, Issue 8, pp. 1100-4, (2010) (PubMed).
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: "SOX9, through interaction with microphthalmia-associated transcription factor (MITF) and OTX2, regulates BEST1 expression in the retinal pigment epithelium." in: The Journal of biological chemistry, Vol. 285, Issue 35, pp. 26933-44, (2010) (PubMed).
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- OTX2 (Orthodenticle Homeobox 2 (OTX2))
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别名
- OTX2
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背景
- This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper forebrain development. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants may exist, but their full length sequences have not been determined.
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分子量
- 31636
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NCBI登录号
- NP_001257452, NP_001257453, NP_001257454, NP_068374, NP_758840
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UniProt
- P32243
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途径
- Dopaminergic Neurogenesis
抗原
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