Netrin 1 抗体 (C-Term)
Quick Overview for Netrin 1 抗体 (C-Term) (ABIN1881590)
抗原
See all Netrin 1 (NTN1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 568-596, C-Term
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预测反应
- C, M, Pig
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This NTN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 568-596 amino acids from the C-terminal region of human NTN1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Systematic mapping and functional analysis of a family of human epididymal secretory sperm-located proteins." in: Molecular & cellular proteomics : MCP, Vol. 9, Issue 11, pp. 2517-28, (2010) (PubMed).
: "DSCAM functions as a netrin receptor in commissural axon pathfinding." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 8, pp. 2951-6, (2009) (PubMed).
: "Netrin-1 controls colorectal tumorigenesis by regulating apoptosis." in: Nature, Vol. 431, Issue 7004, pp. 80-4, (2004) (PubMed).
: "Netrin-1: interaction with deleted in colorectal cancer (DCC) and alterations in brain tumors and neuroblastomas." in: Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, Vol. 10, Issue 1, pp. 35-42, (1999) (PubMed).
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: "Systematic mapping and functional analysis of a family of human epididymal secretory sperm-located proteins." in: Molecular & cellular proteomics : MCP, Vol. 9, Issue 11, pp. 2517-28, (2010) (PubMed).
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- Netrin 1 (NTN1)
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别名
- NTN1
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背景
- Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.
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分子量
- 67748
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NCBI登录号
- NP_004813
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UniProt
- O95631
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途径
- Regulation of Cell Size
抗原
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