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MTAP 抗体 (N-Term)

This anti-MTAP antibody is a 兔 多克隆 antibody detecting MTAP in WB. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN1881557
发货至: 中国

Quick Overview for MTAP 抗体 (N-Term) (ABIN1881557)

抗原

See all MTAP 抗体
MTAP (Methylthioadenosine phosphorylase (MTAP))

适用

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宿主

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克隆类型

  • 48
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多克隆

标记

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This MTAP antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB42759
  • 抗原表位

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    AA 8-37, N-Term

    预测反应

    B, M

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This MTAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-37 amino acids from the N-terminal region of human MTAP.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Newton-Bishop, Chang, Iles, Taylor, Bakker, Chan, Leake, Karpavicius, Haynes, Fitzgibbon, Elliott, Kanetsky, Harland, Barrett, Bishop: "Melanocytic nevi, nevus genes, and melanoma risk in a large case-control study in the United Kingdom." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 8, pp. 2043-54, (2010) (PubMed).

    Zhang, Cheng, Yan, Chen, Wang, Yang: "[Association between methylthioadenosine phosphorylase gene single nucleotide polymorphisms and myocardial infarction in Chinese Han ethnicity]." in: Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, Vol. 31, Issue 1, pp. 83-6, (2010) (PubMed).

    Huang, Li, Yu, Chou, Tzeng, Hu, Uen, Tian, Wang, Fang, Huang, Wei, Wu, Li: "Homozygous deletion of MTAP gene as a poor prognosticator in gastrointestinal stromal tumors." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 22, pp. 6963-72, (2009) (PubMed).

  • 抗原

    MTAP (Methylthioadenosine phosphorylase (MTAP))

    别名

    MTAP

    背景

    This gene encodes an enzyme that plays a major role in polyamine metabolism and is important for the salvage of both adenine and methionine. The encoded enzyme is deficient in many cancers because this gene and the tumor suppressor p16 gene are co-deleted. Multiple alternatively spliced transcript variants have been described for this gene, but their full-length natures remain unknown.

    分子量

    31236

    NCBI登录号

    NP_002442

    UniProt

    Q13126

    途径

    Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
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