MMP26 抗体 (AA 96-125)
Quick Overview for MMP26 抗体 (AA 96-125) (ABIN1881547)
抗原
See all MMP26 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 96-125
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This MMP26 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-125 amino acids from the Central region of human MMP26.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "GnRH I and II up-regulate MMP-26 expression through the JNK pathway in human cytotrophoblasts." in: Reproductive biology and endocrinology : RB&E, Vol. 8, pp. 5, (2010) (PubMed).
: "Matrilysins may not predict the metastatic potential in squamous cell carcinoma of the tongue." in: Acta odontologica Scandinavica, Vol. 68, Issue 4, pp. 228-31, (2010) (PubMed).
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: "GnRH I and II up-regulate MMP-26 expression through the JNK pathway in human cytotrophoblasts." in: Reproductive biology and endocrinology : RB&E, Vol. 8, pp. 5, (2010) (PubMed).
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- MMP26 (Matrix Metallopeptidase 26 (MMP26))
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别名
- MMP26
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背景
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein degrades type IV collagen, fibronectin, fibrinogen, casein, vitronectin, alpha 1-antitrypsin, alpha 2-macroglobulin, and insulin-like growth factor-binding protein 1, and activates MMP9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain.
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分子量
- 29708
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NCBI登录号
- NP_068573
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UniProt
- Q9NRE1
抗原
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