LONP1 抗体 (AA 389-418)
Quick Overview for LONP1 抗体 (AA 389-418) (ABIN1881504)
抗原
See all LONP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 389-418
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预测反应
- B, Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This LONP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-418 amino acids from the Central region of human LONP1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000. WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Splenomegaly as a primary manifestation of Gaucher disease in a young adult woman." in: Case reports in gastroenterology, Vol. 2, Issue 3, pp. 474-8, (2011) (PubMed).
: "Thermodynamic characterization of specific interactions between the human Lon protease and G-quartet DNA." in: Nucleic acids research, Vol. 36, Issue 4, pp. 1273-87, (2008) (PubMed).
: "Towards the control of intracellular protein turnover: mitochondrial Lon protease inhibitors versus proteasome inhibitors." in: Biochimie, Vol. 90, Issue 2, pp. 260-9, (2008) (PubMed).
: "The layered structure of human mitochondrial DNA nucleoids." in: The Journal of biological chemistry, Vol. 283, Issue 6, pp. 3665-75, (2008) (PubMed).
: "[Effect of RNA interference for Lon gene silencing on growth and apoptosis of human breast cancer MCF7 cells]." in: Nan fang yi ke da xue xue bao = Journal of Southern Medical University, Vol. 27, Issue 6, pp. 870-4, (2007) (PubMed).
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: "Splenomegaly as a primary manifestation of Gaucher disease in a young adult woman." in: Case reports in gastroenterology, Vol. 2, Issue 3, pp. 474-8, (2011) (PubMed).
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- LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))
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别名
- LONP1
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背景
- This gene encodes a mitochondrial matrix protein in the Lon family of ATP-dependent proteases. A similar E. coli protein regulates gene expression by targeting specific regulatory proteins for degradation. This protein binds a specific sequence in the light and heavy chain promoters of the mitochondrial genome which are involved in regulation of DNA replication and transcription.
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分子量
- 106489
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NCBI登录号
- NP_001263408, NP_001263409, NP_004784
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UniProt
- P36776
抗原
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