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LONP1 抗体 (AA 389-418)

Cited in 5+ publications. This anti-LONP1 antibody is a 兔 多克隆 antibody detecting LONP1 in WB. Suitable for 人 和 小鼠.
产品编号 ABIN1881504
发货至: 中国
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Quick Overview for LONP1 抗体 (AA 389-418) (ABIN1881504)

抗原

See all LONP1 抗体
LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

适用

  • 41
  • 26
  • 19
  • 1
人, 小鼠

宿主

  • 40
  • 2

克隆类型

  • 40
  • 2
多克隆

标记

  • 13
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This LONP1 antibody is un-conjugated

应用范围

  • 30
  • 17
  • 13
  • 13
  • 6
  • 6
  • 4
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB)

克隆位点

RB40823
  • 抗原表位

    • 15
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 389-418

    预测反应

    B, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This LONP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-418 amino acids from the Central region of human LONP1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000. WB: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Merra, Lago, Ricci, Antuzzi, Gasbarrini, Gasbarrini, Ghirlanda: "Splenomegaly as a primary manifestation of Gaucher disease in a young adult woman." in: Case reports in gastroenterology, Vol. 2, Issue 3, pp. 474-8, (2011) (PubMed).

    Chen, Suzuki, Wu: "Thermodynamic characterization of specific interactions between the human Lon protease and G-quartet DNA." in: Nucleic acids research, Vol. 36, Issue 4, pp. 1273-87, (2008) (PubMed).

    Bayot, Basse, Lee, Gareil, Pirotte, Bulteau, Friguet, Reboud-Ravaux: "Towards the control of intracellular protein turnover: mitochondrial Lon protease inhibitors versus proteasome inhibitors." in: Biochimie, Vol. 90, Issue 2, pp. 260-9, (2008) (PubMed).

    Bogenhagen, Rousseau, Burke: "The layered structure of human mitochondrial DNA nucleoids." in: The Journal of biological chemistry, Vol. 283, Issue 6, pp. 3665-75, (2008) (PubMed).

    Xue, Zhu, Mao: "[Effect of RNA interference for Lon gene silencing on growth and apoptosis of human breast cancer MCF7 cells]." in: Nan fang yi ke da xue xue bao = Journal of Southern Medical University, Vol. 27, Issue 6, pp. 870-4, (2007) (PubMed).

  • 抗原

    LONP1 (Lon Peptidase 1, Mitochondrial (LONP1))

    别名

    LONP1

    背景

    This gene encodes a mitochondrial matrix protein in the Lon family of ATP-dependent proteases. A similar E. coli protein regulates gene expression by targeting specific regulatory proteins for degradation. This protein binds a specific sequence in the light and heavy chain promoters of the mitochondrial genome which are involved in regulation of DNA replication and transcription.

    分子量

    106489

    NCBI登录号

    NP_001263408, NP_001263409, NP_004784

    UniProt

    P36776
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