LHX4 抗体 (AA 133-161)
Quick Overview for LHX4 抗体 (AA 133-161) (ABIN1881496)
抗原
See all LHX4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 133-161
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预测反应
- M
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This LHX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-161 amino acids from the Central region of human LHX4.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "A novel dysfunctional LHX4 mutation with high phenotypical variability in patients with hypopituitarism." in: The Journal of clinical endocrinology and metabolism, Vol. 93, Issue 7, pp. 2790-9, (2008) (PubMed).
: "The C terminus of the synovial sarcoma-associated SSX proteins interacts with the LIM homeobox protein LHX4." in: Oncogene, Vol. 27, Issue 5, pp. 653-62, (2008) (PubMed).
: "Three novel missense mutations within the LHX4 gene are associated with variable pituitary hormone deficiencies." in: The Journal of clinical endocrinology and metabolism, Vol. 93, Issue 3, pp. 1062-71, (2008) (PubMed).
: "Specificity protein 1 (Sp1) plays role in regulating LIM homeodomain transcription factor Lhx4 gene expression." in: Biochemical and biophysical research communications, Vol. 366, Issue 1, pp. 36-41, (2007) (PubMed).
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: "A novel dysfunctional LHX4 mutation with high phenotypical variability in patients with hypopituitarism." in: The Journal of clinical endocrinology and metabolism, Vol. 93, Issue 7, pp. 2790-9, (2008) (PubMed).
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- LHX4 (LIM Homeobox 4 (LHX4))
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别名
- LHX4
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背景
- This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in control of differentiation and development of the pituitary gland. Mutations in this gene are associated with syndromic short stature and pituitary and hindbrain defects. An alternative splice variant has been described but its biological nature has not been determined.
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分子量
- 43124
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NCBI登录号
- NP_203129
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UniProt
- Q969G2
抗原
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