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LHX4 抗体 (AA 133-161)

This anti-LHX4 antibody is a 兔 多克隆 antibody detecting LHX4 in WB. Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN1881496
发货至: 中国

Quick Overview for LHX4 抗体 (AA 133-161) (ABIN1881496)

抗原

See all LHX4 抗体
LHX4 (LIM Homeobox 4 (LHX4))

适用

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宿主

  • 19
  • 6

克隆类型

  • 20
  • 5
多克隆

标记

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This LHX4 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB30670
  • 抗原表位

    • 6
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    AA 133-161

    预测反应

    M

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This LHX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-161 amino acids from the Central region of human LHX4.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Castinetti, Saveanu, Reynaud, Quentien, Buffin, Brauner, Kaffel, Albarel, Guedj, El Kholy, Amin, Enjalbert, Barlier, Brue: "A novel dysfunctional LHX4 mutation with high phenotypical variability in patients with hypopituitarism." in: The Journal of clinical endocrinology and metabolism, Vol. 93, Issue 7, pp. 2790-9, (2008) (PubMed).

    de Bruijn, van Dijk, Willemse, van Kessel: "The C terminus of the synovial sarcoma-associated SSX proteins interacts with the LIM homeobox protein LHX4." in: Oncogene, Vol. 27, Issue 5, pp. 653-62, (2008) (PubMed).

    Pfaeffle, Hunter, Savage, Duran-Prado, Mullen, Neeb, Eiholzer, Hesse, Haddad, Stobbe, Blum, Weigel, Rhodes: "Three novel missense mutations within the LHX4 gene are associated with variable pituitary hormone deficiencies." in: The Journal of clinical endocrinology and metabolism, Vol. 93, Issue 3, pp. 1062-71, (2008) (PubMed).

    Liu, Luo, Liu, McNeilly, Cui: "Specificity protein 1 (Sp1) plays role in regulating LIM homeodomain transcription factor Lhx4 gene expression." in: Biochemical and biophysical research communications, Vol. 366, Issue 1, pp. 36-41, (2007) (PubMed).

  • 抗原

    LHX4 (LIM Homeobox 4 (LHX4))

    别名

    LHX4

    背景

    This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator and be involved in control of differentiation and development of the pituitary gland. Mutations in this gene are associated with syndromic short stature and pituitary and hindbrain defects. An alternative splice variant has been described but its biological nature has not been determined.

    分子量

    43124

    NCBI登录号

    NP_203129

    UniProt

    Q969G2
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