Keratin 86 抗体 (AA 300-327)
KRT86
适用: 人
WB
宿主: 兔
Polyclonal
RB42669
unconjugated
1 image
(4 references)-
- 抗原 See all Keratin 86 (KRT86) 抗体
- Keratin 86 (KRT86)
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抗原表位
- AA 300-327
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Keratin 86 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 预测反应
- Sh, B, M
- 纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- 免疫原
- This KRT86 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 300-327 amino acids from the Central region of human KRT86.
- 克隆位点
- RB42669
- 亚型
- Ig Fraction
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- 应用备注
- WB: 1:1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 有效期
- 6 months
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: "Mutation E402K of the hHb6 in a Chinese Han family with monilethrix." in: European journal of dermatology : EJD, Vol. 19, Issue 5, pp. 508-9, (2009) (PubMed).
: "[Analysis of human hair basic keratin 6 gene mutation in a Chinese Han family with monilethrix]." in: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, Vol. 25, Issue 2, pp. 141-4, (2008) (PubMed).
: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, (2007) (PubMed).
: "New consensus nomenclature for mammalian keratins." in: The Journal of cell biology, Vol. 174, Issue 2, pp. 169-74, (2006) (PubMed).
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: "Mutation E402K of the hHb6 in a Chinese Han family with monilethrix." in: European journal of dermatology : EJD, Vol. 19, Issue 5, pp. 508-9, (2009) (PubMed).
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- 抗原
- Keratin 86 (KRT86)
- 别名
- KRT86 (KRT86 产品)
- 别名
- Kb26 antibody, KRT86 antibody, HB6 antibody, Hb1 antibody, KRTHB1 antibody, KRTHB6 antibody, MNX antibody, hHb6 antibody, 5430421N21Rik antibody, AI325212 antibody, Khb4 antibody, Krt2-10 antibody, Krt2-11 antibody, MHb4 antibody, keratin 86 antibody, hair keratin type II intermediate filament antibody, Krt86 antibody, KRT86 antibody, KRT2.11 antibody
- 背景
- The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle, this hair keratin, as well as KRTHB1 and KRTHB3, is found primarily in the hair cortex. Mutations in this gene and KRTHB1 have been observed in patients with a rare dominant hair disease, monilethrix.
- 分子量
- 53501
- NCBI登录号
- NP_002275
- UniProt
- O43790
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