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KRT6A 抗体 (AA 212-240)

This anti-KRT6A antibody is a 兔 多克隆 antibody detecting KRT6A in WB. Suitable for 小鼠. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN1881486
发货至: 中国

Quick Overview for KRT6A 抗体 (AA 212-240) (ABIN1881486)

抗原

See all KRT6A 抗体
KRT6A (Keratin 6A (KRT6A))

适用

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小鼠

宿主

  • 65
  • 34
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克隆类型

  • 62
  • 39
多克隆

标记

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This KRT6A antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB40714
  • 抗原表位

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    AA 212-240

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This Mouse Krt6a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-240 amino acids from the Central region of mouse Krt6a.

    亚型

    IgG
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Sehic, Khuu, Risnes, Osmundsen et al.: "Differential gene expression profiling of the molar tooth germ in peroxisome proliferator-activated receptor-alpha (PPAR-alpha) knockout mouse and in wild-type mouse: molar tooth phenotype of..." in: European journal of oral sciences, Vol. 117, Issue 2, pp. 93-104, (2009) (PubMed).

    Chen, Jaeger, Den, Koch, Sundberg, Roop: "Mice expressing a mutant Krt75 (K6hf) allele develop hair and nail defects resembling pachyonychia congenita." in: The Journal of investigative dermatology, Vol. 128, Issue 2, pp. 270-9, (2008) (PubMed).

    Cui, Kunisada, Esibizione, Grivennikov, Piao, Nedospasov, Schlessinger: "Lymphotoxin-beta regulates periderm differentiation during embryonic skin development." in: Human molecular genetics, Vol. 16, Issue 21, pp. 2583-90, (2007) (PubMed).

    Gu, Coulombe: "Keratin expression provides novel insight into the morphogenesis and function of the companion layer in hair follicles." in: The Journal of investigative dermatology, Vol. 127, Issue 5, pp. 1061-73, (2007) (PubMed).

    Kurek, Garinis, van Doorninck, van der Wees, Grosveld: "Transcriptome and phenotypic analysis reveals Gata3-dependent signalling pathways in murine hair follicles." in: Development (Cambridge, England), Vol. 134, Issue 2, pp. 261-72, (2006) (PubMed).

  • 抗原

    KRT6A (Keratin 6A (KRT6A))

    别名

    Krt6a

    背景

    Keratins 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyperproliferation related keratins). Keratin 6 is found in hair follicles, neck squamous cell carcinomas, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyperproliferative situations. Epidermal injury results in activation of keratinocytes which express CK6 and CK16. CK6 is strongly expressed in about 75 % of head and neck squamous cell carcinomas. Expression of CK6 is particularly associated with differentiation. There are at least six isoforms of human type II keratin 6 (K6), K6A being the most abundant representing about 77 % of all forms found in epithelia.

    分子量

    59335

    NCBI登录号

    NP_032502

    UniProt

    P50446
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