PDX1 抗体 (AA 43-72)
Quick Overview for PDX1 抗体 (AA 43-72) (ABIN1881463)
抗原
See all PDX1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 43-72
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预测反应
- M, Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This IPF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-72 amino acids from human IPF.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Pancreatic duodenal homeobox-1 (PDX1) functions as a tumor suppressor in gastric cancer." in: Carcinogenesis, Vol. 29, Issue 7, pp. 1327-33, (2008) (PubMed).
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: "Pancreatic duodenal homeobox-1 (PDX1) functions as a tumor suppressor in gastric cancer." in: Carcinogenesis, Vol. 29, Issue 7, pp. 1327-33, (2008) (PubMed).
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- PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))
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别名
- IPF
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背景
- IPF is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. This nuclear protein is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in this gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
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分子量
- 30771
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NCBI登录号
- NP_000200
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UniProt
- P52945
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途径
- Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location
抗原
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