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ICT1 抗体 (C-Term)

Cited in 5+ publications. The 兔 多克隆 anti-ICT1 antibody (Clone RB42881) (ABIN1881444) specifically detects ICT1 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN1881444
发货至: 中国
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Quick Overview for ICT1 抗体 (C-Term) (ABIN1881444)

抗原

See all ICT1 抗体
ICT1 (Immature Colon Carcinoma Transcript 1 (ICT1))

适用

  • 33
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1

宿主

  • 25
  • 8

克隆类型

  • 27
  • 6
多克隆

标记

  • 17
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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ICT1 antibody is un-conjugated

应用范围

  • 30
  • 13
  • 13
  • 9
  • 4
  • 3
  • 2
  • 2
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  • 1
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  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB42881
  • 抗原表位

    • 15
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 153-179, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This ICT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-179 amino acids from the C-terminal region of human ICT1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:25. IHC-P: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Wang, He, Zhang, Yang, Wang, Liu, Wu: "Knockdown of Immature Colon Carcinoma Transcript 1 Inhibits Proliferation and Promotes Apoptosis of Non-Small Cell Lung Cancer Cells." in: Technology in cancer research & treatment, Vol. 16, Issue 5, pp. 559-569, (2018) (PubMed).

    Tao, Song, Han, Wang, Zhao, Gu: "miR-205 regulation of ICT1 has an oncogenic potential via promoting the migration and invasion of gastric cancer cells." in: Biomedicine & pharmacotherapy, Vol. 96, pp. 191-197, (2018) (PubMed).

    Wang, Jin, Wu, Wang, Li: "Immature colon carcinoma transcript-1 promotes proliferation of gastric cancer cells." in: Acta biochimica et biophysica Sinica, Vol. 49, Issue 11, pp. 979-988, (2018) (PubMed).

    Chang, Yu, Tian, Lin: "Immature colon carcinoma transcript-1 promotes cell growth of hepatocellular carcinoma via facilitating cell cycle progression and apoptosis resistance." in: Oncology reports, Vol. 38, Issue 6, pp. 3489-3496, (2018) (PubMed).

    Xie, Zhang, Shen, Cao, Gu, Che: "Knockdown of immature colon carcinoma transcript-1 inhibits proliferation of glioblastoma multiforme cells through Gap 2/mitotic phase arrest." in: OncoTargets and therapy, Vol. 8, pp. 1119-27, (2015) (PubMed).

  • 抗原

    ICT1 (Immature Colon Carcinoma Transcript 1 (ICT1))

    别名

    ICT1

    背景

    Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.

    分子量

    23630

    NCBI登录号

    NP_001536

    UniProt

    Q14197
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