HIST2H3A 抗体 (C-Term)
(5 references)Quick Overview for HIST2H3A 抗体 (C-Term) (ABIN1881419)
抗原
See all HIST2H3A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 108-136, C-Term
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预测反应
- B, M, Rat, C, Zf, X, E, D, Pig, Rb
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This HIST2H3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-136 amino acids from the C-terminal region of human HIST2H3A.
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亚型
- Ig Fraction
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anti-Histone Cluster 2, H3a (HIST2H3A) (AA 1-136) antibody
HIST2H3A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Histone Cluster 2, H3a (HIST2H3A) (AA 108-136) antibodyHIST2H3A 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Histone Cluster 2, H3a (HIST2H3A) (AA 1-136) antibodyHIST2H3A 适用: 小鼠 WB, IHC, ELISA, IF/ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "A method for genetically installing site-specific acetylation in recombinant histones defines the effects of H3 K56 acetylation." in: Molecular cell, Vol. 36, Issue 1, pp. 153-63, (2009) (PubMed).
: "Phosphorylation of histone H3 Thr-45 is linked to apoptosis." in: The Journal of biological chemistry, Vol. 284, Issue 24, pp. 16575-83, (2009) (PubMed).
: "Histone H3-K56 acetylation is important for genomic stability in mammals." in: Cell cycle (Georgetown, Tex.), Vol. 8, Issue 11, pp. 1747-53, (2009) (PubMed).
: "Sustained JNK1 activation is associated with altered histone H3 methylations in human liver cancer." in: Journal of hepatology, Vol. 50, Issue 2, pp. 323-33, (2009) (PubMed).
: "Prokaryotic BirA ligase biotinylates K4, K9, K18 and K23 in histone H3." in: BMB reports, Vol. 41, Issue 4, pp. 310-5, (2008) (PubMed).
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: "A method for genetically installing site-specific acetylation in recombinant histones defines the effects of H3 K56 acetylation." in: Molecular cell, Vol. 36, Issue 1, pp. 153-63, (2009) (PubMed).
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- HIST2H3A (Histone Cluster 2, H3a (HIST2H3A))
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别名
- HIST2H3A
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背景
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated, this record represents the telomeric copy. [provided by RefSeq].
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分子量
- 15388
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NCBI登录号
- NP_001005464, NP_001116847, NP_066403
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UniProt
- Q71DI3
抗原
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