HIST2H2AC 抗体 (AA 18-46)
Quick Overview for HIST2H2AC 抗体 (AA 18-46) (ABIN1881417)
抗原
See all HIST2H2AC 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 18-46
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预测反应
- Rat, B, X, M, C, Pr, Zf, D
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This HIST2H2AC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the Central region of human HIST2H2AC.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Acetylation of vertebrate H2A.Z and its effect on the structure of the nucleosome." in: Biochemistry, Vol. 48, Issue 22, pp. 5007-17, (2009) (PubMed).
: "Truncation of histone H2A's C-terminal tail, as is typical for Ni(II)-assisted specific peptide bond hydrolysis, has gene expression altering effects." in: Annals of clinical and laboratory science, Vol. 39, Issue 3, pp. 251-62, (2009) (PubMed).
: "A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing." in: Molecular cell, Vol. 29, Issue 1, pp. 92-101, (2008) (PubMed).
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: "Acetylation of vertebrate H2A.Z and its effect on the structure of the nucleosome." in: Biochemistry, Vol. 48, Issue 22, pp. 5007-17, (2009) (PubMed).
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- HIST2H2AC (Histone Cluster 2, H2ac (HIST2H2AC))
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别名
- HIST2H2AC
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背景
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family.
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分子量
- 13988
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NCBI登录号
- NP_003508
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UniProt
- Q16777
抗原
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