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HIST2H2AC 抗体 (AA 18-46)

This anti-HIST2H2AC antibody is a 兔 多克隆 antibody detecting HIST2H2AC in WB. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN1881417
发货至: 中国

Quick Overview for HIST2H2AC 抗体 (AA 18-46) (ABIN1881417)

抗原

See all HIST2H2AC 抗体
HIST2H2AC (Histone Cluster 2, H2ac (HIST2H2AC))

适用

  • 24
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  • 1
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宿主

  • 24

克隆类型

  • 24
多克隆

标记

  • 8
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  • 2
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This HIST2H2AC antibody is un-conjugated

应用范围

  • 19
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Western Blotting (WB)

克隆位点

RB41799
  • 抗原表位

    • 6
    • 5
    • 5
    • 2
    AA 18-46

    预测反应

    Rat, B, X, M, C, Pr, Zf, D

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This HIST2H2AC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-46 amino acids from the Central region of human HIST2H2AC.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Ishibashi, Dryhurst, Rose, Shabanowitz, Hunt, Ausió: "Acetylation of vertebrate H2A.Z and its effect on the structure of the nucleosome." in: Biochemistry, Vol. 48, Issue 22, pp. 5007-17, (2009) (PubMed).

    Karaczyn, Cheng, Buzard, Hartley, Esposito, Kasprzak: "Truncation of histone H2A's C-terminal tail, as is typical for Ni(II)-assisted specific peptide bond hydrolysis, has gene expression altering effects." in: Annals of clinical and laboratory science, Vol. 39, Issue 3, pp. 251-62, (2009) (PubMed).

    Zhao, Lang, Ito, Bonnet, Metzger, Sawatsubashi, Suzuki, Le Guezennec, Stunnenberg, Krasnov, Georgieva, Schüle, Takeyama, Kato, Tora, Devys: "A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing." in: Molecular cell, Vol. 29, Issue 1, pp. 92-101, (2008) (PubMed).

  • 抗原

    HIST2H2AC (Histone Cluster 2, H2ac (HIST2H2AC))

    别名

    HIST2H2AC

    背景

    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family.

    分子量

    13988

    NCBI登录号

    NP_003508

    UniProt

    Q16777
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