HIST1H2BJ,HIST1H2BK,HIST3H2BB (AA 98-126), (C-Term) 抗体
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Quick Overview for HIST1H2BJ,HIST1H2BK,HIST3H2BB (AA 98-126), (C-Term) 抗体 (ABIN1881414)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 98-126, C-Term
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预测反应
- X, B, Pr, M
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This HIST1H2BJ/HIST1H2BK/HIST3H2BB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the C-terminal region of human HIST1H2BJ/HIST1H2BK/HIST3H2BB.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Common variants on chromosome 6p22.1 are associated with schizophrenia." in: Nature, Vol. 460, Issue 7256, pp. 753-7, (2009) (PubMed).
: "Variants in TF and HFE explain approximately 40% of genetic variation in serum-transferrin levels." in: American journal of human genetics, Vol. 84, Issue 1, pp. 60-5, (2009) (PubMed).
: "Quantitative proteomic analysis of post-translational modifications of human histones." in: Molecular & cellular proteomics : MCP, Vol. 5, Issue 7, pp. 1314-25, (2006) (PubMed).
: "Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II." in: Cell, Vol. 125, Issue 4, pp. 703-17, (2006) (PubMed).
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- HIST1H2BJ,HIST1H2BK,HIST3H2BB
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背景
- Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq].
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分子量
- 13904
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NCBI登录号
- NP_066402
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UniProt
- P06899
抗原
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