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GUCA1C 抗体 (C-Term)

Cited in 3+ publications. This 兔 多克隆 anti-GUCA1C antibody (Clone RB42656) specifically detects GUCA1C in WB. The antibody is reactive with 人 samples.
产品编号 ABIN1881400
发货至: 中国
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Quick Overview for GUCA1C 抗体 (C-Term) (ABIN1881400)

抗原

See all GUCA1C 抗体
GUCA1C (Guanylate Cyclase Activator 1C (GUCA1C))

适用

宿主

  • 25
  • 2

克隆类型

  • 26
  • 1
多克隆

标记

  • 8
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  • 1
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This GUCA1C antibody is un-conjugated

应用范围

  • 27
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Western Blotting (WB)

克隆位点

RB42656
  • 抗原表位

    • 15
    • 8
    • 3
    • 1
    • 1
    AA 171-199, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This GUCA1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-199 amino acids from the C-terminal region of human GUCA1C.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Stephen, Palczewski, Sousa: "The crystal structure of GCAP3 suggests molecular mechanism of GCAP-linked cone dystrophies." in: Journal of molecular biology, Vol. 359, Issue 2, pp. 266-75, (2006) (PubMed).

    Imanishi, Li, Sokal, Sowa, Lichtarge, Wensel, Saperstein, Baehr, Palczewski: "Characterization of retinal guanylate cyclase-activating protein 3 (GCAP3) from zebrafish to man." in: The European journal of neuroscience, Vol. 15, Issue 1, pp. 63-78, (2002) (PubMed).

    Haeseleer, Sokal, Li, Pettenati, Rao, Bronson, Wechter, Baehr, Palczewski: "Molecular characterization of a third member of the guanylyl cyclase-activating protein subfamily." in: The Journal of biological chemistry, Vol. 274, Issue 10, pp. 6526-35, (1999) (PubMed).

  • 抗原

    GUCA1C (Guanylate Cyclase Activator 1C (GUCA1C))

    别名

    GUCA1C

    背景

    GUCA1C stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure.

    分子量

    23822

    NCBI登录号

    NP_005450

    UniProt

    O95843

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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