GUCA1C 抗体 (C-Term)
Quick Overview for GUCA1C 抗体 (C-Term) (ABIN1881400)
抗原
See all GUCA1C 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 171-199, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This GUCA1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-199 amino acids from the C-terminal region of human GUCA1C.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "The crystal structure of GCAP3 suggests molecular mechanism of GCAP-linked cone dystrophies." in: Journal of molecular biology, Vol. 359, Issue 2, pp. 266-75, (2006) (PubMed).
: "Characterization of retinal guanylate cyclase-activating protein 3 (GCAP3) from zebrafish to man." in: The European journal of neuroscience, Vol. 15, Issue 1, pp. 63-78, (2002) (PubMed).
: "Molecular characterization of a third member of the guanylyl cyclase-activating protein subfamily." in: The Journal of biological chemistry, Vol. 274, Issue 10, pp. 6526-35, (1999) (PubMed).
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: "The crystal structure of GCAP3 suggests molecular mechanism of GCAP-linked cone dystrophies." in: Journal of molecular biology, Vol. 359, Issue 2, pp. 266-75, (2006) (PubMed).
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- GUCA1C (Guanylate Cyclase Activator 1C (GUCA1C))
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别名
- GUCA1C
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背景
- GUCA1C stimulates guanylyl cyclase 1 (GC1) and GC2 when free calcium ions concentration is low and inhibits guanylyl cyclases when free calcium ions concentration is elevated. This Ca(2+)-sensitive regulation of guanylyl cyclase (GC) is a key event in recovery of the dark state of rod photoreceptors following light exposure.
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分子量
- 23822
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NCBI登录号
- NP_005450
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UniProt
- O95843
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
抗原
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