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GUCA1B 抗体 (N-Term)

Cited in 3+ publications. The 兔 多克隆 anti-GUCA1B antibody (Clone RB40485) (ABIN1881399) specifically detects GUCA1B in WB. The antibody is reactive with 人 samples.
产品编号 ABIN1881399
发货至: 中国
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Quick Overview for GUCA1B 抗体 (N-Term) (ABIN1881399)

抗原

See all GUCA1B 抗体
GUCA1B (Guanylate Cyclase Activator 1B (Retina) (GUCA1B))

适用

  • 20
  • 10
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  • 2
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  • 1
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宿主

  • 19
  • 1

克隆类型

  • 19
  • 1
多克隆

标记

  • 8
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GUCA1B antibody is un-conjugated

应用范围

  • 13
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Western Blotting (WB)

克隆位点

RB40485
  • 抗原表位

    • 8
    • 2
    • 1
    • 1
    • 1
    AA 29-57, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This GUCA1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human GUCA1B.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Sato, Nakazawa, Usui, Tanimoto, Abe, Ohguro: "Mutations in the gene coding for guanylate cyclase-activating protein 2 (GUCA1B gene) in patients with autosomal dominant retinal dystrophies." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 243, Issue 3, pp. 235-42, (2005) (PubMed).

    Nishiguchi, Sokal, Yang, Roychowdhury, Palczewski, Berson, Dryja, Baehr: "A novel mutation (I143NT) in guanylate cyclase-activating protein 1 (GCAP1) associated with autosomal dominant cone degeneration." in: Investigative ophthalmology & visual science, Vol. 45, Issue 11, pp. 3863-70, (2004) (PubMed).

    Mungall, Palmer, Sims, Edwards, Ashurst, Wilming, Jones, Horton, Hunt, Scott, Gilbert, Clamp, Bethel, Milne, Ainscough, Almeida, Ambrose, Andrews, Ashwell, Babbage, Bagguley, Bailey, Banerjee, Barker et al.: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, (2003) (PubMed).

  • 抗原

    GUCA1B (Guanylate Cyclase Activator 1B (Retina) (GUCA1B))

    别名

    GUCA1B

    背景

    The protein encoded by this gene is a calcium-binding protein that activates photoreceptor guanylate cyclases. This gene may have arisen due to a gene duplication event since there is a highly similar gene clustered with it on chromosome 6. Mutations in this gene can cause a form of retinitis pigmentosa. [provided by RefSeq].

    分子量

    23420

    NCBI登录号

    NP_002089

    UniProt

    Q9UMX6

    途径

    Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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