GUCA1B 抗体 (N-Term)
Quick Overview for GUCA1B 抗体 (N-Term) (ABIN1881399)
抗原
See all GUCA1B 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 29-57, N-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This GUCA1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human GUCA1B.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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Mutations in the gene coding for guanylate cyclase-activating protein 2 (GUCA1B gene) in patients with autosomal dominant retinal dystrophies." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 243, Issue 3, pp. 235-42, (2005) (PubMed).
: "A novel mutation (I143NT) in guanylate cyclase-activating protein 1 (GCAP1) associated with autosomal dominant cone degeneration." in: Investigative ophthalmology & visual science, Vol. 45, Issue 11, pp. 3863-70, (2004) (PubMed).
: "The DNA sequence and analysis of human chromosome 6. ..." in: Nature, Vol. 425, Issue 6960, pp. 805-11, (2003) (PubMed).
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Mutations in the gene coding for guanylate cyclase-activating protein 2 (GUCA1B gene) in patients with autosomal dominant retinal dystrophies." in: Graefe's archive for clinical and experimental ophthalmology, Vol. 243, Issue 3, pp. 235-42, (2005) (PubMed).
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- GUCA1B (Guanylate Cyclase Activator 1B (Retina) (GUCA1B))
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别名
- GUCA1B
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背景
- The protein encoded by this gene is a calcium-binding protein that activates photoreceptor guanylate cyclases. This gene may have arisen due to a gene duplication event since there is a highly similar gene clustered with it on chromosome 6. Mutations in this gene can cause a form of retinitis pigmentosa. [provided by RefSeq].
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分子量
- 23420
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NCBI登录号
- NP_002089
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UniProt
- Q9UMX6
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
抗原
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