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GTPBP3 抗体 (AA 293-320)

This anti-GTPBP3 antibody is a 兔 多克隆 antibody detecting GTPBP3 in WB. Suitable for 人. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN1881398
发货至: 中国

Quick Overview for GTPBP3 抗体 (AA 293-320) (ABIN1881398)

抗原

See all GTPBP3 抗体
GTPBP3 (GTP Binding Protein 3 (Mitochondrial) (GTPBP3))

适用

  • 13
  • 1
  • 1

宿主

  • 12
  • 1

克隆类型

  • 13
多克隆

标记

  • 8
  • 1
  • 1
  • 1
  • 1
  • 1
This GTPBP3 antibody is un-conjugated

应用范围

  • 12
  • 10
  • 4
  • 1
Western Blotting (WB)

克隆位点

RB40710
  • 抗原表位

    • 6
    • 1
    • 1
    • 1
    • 1
    AA 293-320

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This GTPBP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-320 amino acids from the Central region of human GTPBP3.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Reiling, van Vliet-Ostaptchouk, van t Riet, van Haeften, Arp, Hansen, Kremer, Groenewoud, van Hove, Romijn, Smit, Nijpels, Heine, Uitterlinden, Pedersen, Slagboom, Maassen, Hofker, t Hart, Dekker: "Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study." in: European journal of human genetics : EJHG, Vol. 17, Issue 8, pp. 1056-62, (2009) (PubMed).

    Villarroya, Prado, Esteve, Soriano, Aguado, Pérez-Martínez, Martínez-Ferrandis, Yim, Victor, Cebolla, Montaner, Knecht, Armengod: "Characterization of human GTPBP3, a GTP-binding protein involved in mitochondrial tRNA modification." in: Molecular and cellular biology, Vol. 28, Issue 24, pp. 7514-31, (2008) (PubMed).

    Bykhovskaya, Mengesha, Wang, Yang, Estivill, Shohat, Fischel-Ghodsian: "Phenotype of non-syndromic deafness associated with the mitochondrial A1555G mutation is modulated by mitochondrial RNA modifying enzymes MTO1 and GTPBP3." in: Molecular genetics and metabolism, Vol. 83, Issue 3, pp. 199-206, (2004) (PubMed).

    Li, Guan: "Identification and characterization of mouse GTPBP3 gene encoding a mitochondrial GTP-binding protein involved in tRNA modification." in: Biochemical and biophysical research communications, Vol. 312, Issue 3, pp. 747-54, (2003) (PubMed).

    Li, Guan: "A human mitochondrial GTP binding protein related to tRNA modification may modulate phenotypic expression of the deafness-associated mitochondrial 12S rRNA mutation." in: Molecular and cellular biology, Vol. 22, Issue 21, pp. 7701-11, (2002) (PubMed).

  • 抗原

    GTPBP3 (GTP Binding Protein 3 (Mitochondrial) (GTPBP3))

    别名

    GTPBP3

    背景

    This locus encodes a GTP-binding protein. The encoded protein is localized to the mitochondria and may play a role in mitochondrial tRNA modification. Polymorphisms at this locus may be associated with severity of aminoglycoside-induced deafness, a disease associated with a mutation in the 12S rRNA. Alternatively spliced transcript variants encoding different isoforms have been described.

    分子量

    52058

    NCBI登录号

    NP_001122327, NP_001182351, NP_116009, NP_598399

    UniProt

    Q969Y2
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