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GATM 抗体 (C-Term)

There are 3+ publications for this product available. The 兔 多克隆 anti-GATM antibody is suitable to detect GATM in samples from 人. It has been validated for WB.
产品编号 ABIN1881365
发货至: 中国
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Quick Overview for GATM 抗体 (C-Term) (ABIN1881365)

抗原

See all GATM 抗体
GATM (Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM))

适用

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宿主

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克隆类型

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多克隆

标记

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This GATM antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB41023
  • 抗原表位

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    AA 350-378, C-Term

    预测反应

    B, Pr, M, Pig, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This GATM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 350-378 amino acids from the C-terminal region of human GATM.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Köttgen, Glazer, Dehghan, Hwang, Katz, Li, Yang, Gudnason, Launer, Harris, Smith, Arking, Astor, Boerwinkle, Ehret, Ruczinski: "Multiple loci associated with indices of renal function and chronic kidney disease." in: Nature genetics, Vol. 41, Issue 6, pp. 712-7, (2010) (PubMed).

    Köttgen, Pattaro, Böger, Fuchsberger, Olden, Glazer, Parsa, Gao, Yang, Smith, OConnell, Li, Schmidt, Tanaka, Isaacs, Ketkar, Hwang, Johnson, Dehghan, Teumer, Paré, Atkinson, Zeller, Lohman et al.: "New loci associated with kidney function and chronic kidney disease...." in: Nature genetics, Vol. 42, Issue 5, pp. 376-84, (2010) (PubMed).

    Lion-François, Cheillan, Pitelet, Acquaviva-Bourdain, Bussy, Cotton, Guibaud, Gérard, Rivier, Vianey-Saban, Jakobs, Salomons, des Portes: "High frequency of creatine deficiency syndromes in patients with unexplained mental retardation." in: Neurology, Vol. 67, Issue 9, pp. 1713-4, (2006) (PubMed).

  • 抗原

    GATM (Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM))

    别名

    GATM

    背景

    This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.

    分子量

    48455

    NCBI登录号

    NP_001473

    UniProt

    P50440
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