GAR1 抗体 (AA 86-114)
Quick Overview for GAR1 抗体 (AA 86-114) (ABIN1881363)
抗原
See all GAR1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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                                            抗原表位
- AA 86-114
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                                            预测反应
- Zf, Rat
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                                            纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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                                            免疫原
- This GAR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-114 amino acids from the Central region of human GAR1.
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                                            亚型
- Ig Fraction
 
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                                            应用备注
- WB: 1:1000
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-20 °C
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                                            有效期
- 6 months
 
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                                            : "The box H/ACA ribonucleoprotein complex: interplay of RNA and protein structures in post-transcriptional RNA modification."    in: The Journal of biological chemistry, Vol. 285, Issue 2, pp. 805-9, (2010)         (PubMed).        
 : "A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts." in: Human molecular genetics, Vol. 19, Issue 12, pp. 2497-506, (2010) (PubMed).
 : "NOLA1 gene mutations in acquired aplastic anemia." in: Pediatric blood & cancer, Vol. 52, Issue 3, pp. 376-8, (2009) (PubMed).
 
 
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                                            : "The box H/ACA ribonucleoprotein complex: interplay of RNA and protein structures in post-transcriptional RNA modification."    in: The Journal of biological chemistry, Vol. 285, Issue 2, pp. 805-9, (2010)         (PubMed).        
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    - GAR1 (GAR1 Ribonucleoprotein Homolog (Yeast) (GAR1))
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                                            别名
- GAR1
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                                            背景
- This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA2 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. These four H/ACA snoRNP proteins are also components of the telomerase complex. The encoded protein of this gene contains two glycine- and arginine-rich domains and is related to Saccharomyces cerevisiae Gar1p. Two splice variants have been found for this gene.
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                                            分子量
- 22348
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                                            NCBI登录号
- NP_061856, NP_127460
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                                            UniProt
- Q9NY12
 抗原
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