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GAR1 抗体 (AA 86-114)

Cited in 3+ publications. The 兔 多克隆 anti-GAR1 antibody (Clone RB39831) (ABIN1881363) specifically detects GAR1 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN1881363
发货至: 中国
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Quick Overview for GAR1 抗体 (AA 86-114) (ABIN1881363)

抗原

See all GAR1 抗体
GAR1 (GAR1 Ribonucleoprotein Homolog (Yeast) (GAR1))

适用

  • 26
  • 5
  • 3

宿主

  • 25
  • 1

克隆类型

  • 26
多克隆

标记

  • 11
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  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GAR1 antibody is un-conjugated

应用范围

  • 16
  • 15
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  • 1
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Western Blotting (WB)

克隆位点

RB39831
  • 抗原表位

    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 86-114

    预测反应

    Zf, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This GAR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-114 amino acids from the Central region of human GAR1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Hamma, Ferré-DAmaré: "The box H/ACA ribonucleoprotein complex: interplay of RNA and protein structures in post-transcriptional RNA modification." in: The Journal of biological chemistry, Vol. 285, Issue 2, pp. 805-9, (2010) (PubMed).

    Kalsi, Kuo, Aliev, Alexander, McMichael, Patterson, Walsh, Zhao, Schuckit, Nurnberger, Edenberg, Kramer, Hesselbrock, Tischfield, Vladimirov, Prescott, Dick, Kendler, Riley: "A systematic gene-based screen of chr4q22-q32 identifies association of a novel susceptibility gene, DKK2, with the quantitative trait of alcohol dependence symptom counts." in: Human molecular genetics, Vol. 19, Issue 12, pp. 2497-506, (2010) (PubMed).

    Pigullo, Pavesi, Dianzani, Santamaria, Svahn, Risso, Van Lint, Pillon, Iori, Longoni, Ramenghi, Lanciotti, Dufour: "NOLA1 gene mutations in acquired aplastic anemia." in: Pediatric blood & cancer, Vol. 52, Issue 3, pp. 376-8, (2009) (PubMed).

  • 抗原

    GAR1 (GAR1 Ribonucleoprotein Homolog (Yeast) (GAR1))

    别名

    GAR1

    背景

    This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA2 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. These four H/ACA snoRNP proteins are also components of the telomerase complex. The encoded protein of this gene contains two glycine- and arginine-rich domains and is related to Saccharomyces cerevisiae Gar1p. Two splice variants have been found for this gene.

    分子量

    22348

    NCBI登录号

    NP_061856, NP_127460

    UniProt

    Q9NY12
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