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Frataxin 抗体 (N-Term)

Name: Frataxin 抗体 (N-Term)
SKU: ABIN1881356
Availability: OutOfStock

This anti-Frataxin antibody is a 兔多克隆 antibody detecting Frataxin in WB. Suitable for 人. This Primary Antibody has been cited in 4+ publications.

Anti-FXN Antibody (N-term) at 1:1000 dilution + CCRF-CEM whole cell lysate Lysates/proteins at 20 μg per lane. (Frataxin 抗体 (N-Term))

1 image

(4 references)

产品编号 ABIN1881356

发货至: 中国

Quick Overview for Frataxin 抗体 (N-Term) (ABIN1881356)

抗原

See all Frataxin (FXN) 抗体

Frataxin (FXN)

适用

人

宿主

兔

克隆类型

多克隆

标记

This Frataxin antibody is un-conjugated

应用范围

Western Blotting (WB)

克隆位点

RB41914

Discover our top product FXN Primary Antibody

抗原表位
8

8

7

7

5

4

4

3

3

2

1

1

1

1

1
AA 36-64, N-Term

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This FXN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the N-terminal region of human FXN.

亚型

Ig Fraction
anti-Frataxin (FXN) (AA 57-210) antibody
FXN 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal FXN-2124 unconjugated

anti-Frataxin (FXN) (AA 42-210) antibody
FXN 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Frataxin (FXN) (AA 91-200) antibody
FXN 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 3G9 unconjugated

anti-Frataxin (FXN) (AA 91-200) antibody
FXN 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1D9 unconjugated

anti-Frataxin (FXN) (AA 41-207) antibody
FXN 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Frataxin (FXN) (AA 1-210) antibody
FXN 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Frataxin (FXN) (AA 1-210) antibody
FXN 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Frataxin (FXN) (AA 105-154) antibody
FXN 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, 犬, 豚鼠, 猴, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Frataxin (FXN) (Internal Region) antibody
FXN 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Frataxin (FXN) (AA 72-102) antibody
FXN 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB12541 unconjugated

应用备注

WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Tsai, Barondeau: "Human frataxin is an allosteric switch that activates the Fe-S cluster biosynthetic complex." in: Biochemistry, Vol. 49, Issue 43, pp. 9132-9, (2010) (PubMed).

Thierbach, Drewes, Fusser, Voigt, Kuhlow, Blume, Schulz, Reiche, Glatt, Epe, Steinberg, Ristow: "The Friedreich's ataxia protein frataxin modulates DNA base excision repair in prokaryotes and mammals." in: The Biochemical journal, Vol. 432, Issue 1, pp. 165-72, (2010) (PubMed).

Mariño, Zaldivar, Mesa, Mederos, Rodríguez, Gotay, Labrada, Ochoa, Macleod, Pérez: "Low predisposition to instability of the Friedreich ataxia gene in Cuban population." in: Clinical genetics, Vol. 77, Issue 6, pp. 598-600, (2010) (PubMed).

Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).
抗原

Frataxin (FXN)

别名

FXN

背景

This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants.

分子量

23135

NCBI登录号

NP_000135, NP_001155178, NP_852090

UniProt

Q16595

途径

Transition Metal Ion Homeostasis, Regulation of Cell Size