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FCRL3 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects FCRL3 in WB. It exhibits reactivity toward 人. It has been mentioned in 4+ publications
产品编号 ABIN1881343
发货至: 中国
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Quick Overview for FCRL3 抗体 (C-Term) (ABIN1881343)

抗原

See all FCRL3 抗体
FCRL3 (Fc Receptor-Like 3 (FCRL3))

适用

  • 12
  • 2
  • 2

宿主

  • 8
  • 4

克隆类型

  • 8
  • 4
多克隆

标记

  • 8
  • 1
  • 1
  • 1
  • 1
This FCRL3 antibody is un-conjugated

应用范围

  • 5
  • 5
  • 4
  • 3
  • 1
Western Blotting (WB)

克隆位点

RB41960
  • 抗原表位

    • 4
    • 2
    • 1
    • 1
    AA 694-720, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This FCRL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 694-720 amino acids from the C-terminal region of human FCRL3.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Swainson, Mold, Bajpai, McCune: "Expression of the autoimmune susceptibility gene FcRL3 on human regulatory T cells is associated with dysfunction and high levels of programmed cell death-1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 7, pp. 3639-47, (2010) (PubMed).

    Davila, Froeling, Tan, Bonnard, Boland, Snippe, Hibberd, Seielstad: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).

    Zheng, Zhao, Zhang, Li: "[Study on the association of 3 SNPs of FcRL3 gene with Graves disease in Chongqing Han population]." in: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, Vol. 26, Issue 6, pp. 681-5, (2009) (PubMed).

    Gibson, Li, Wu, Edberg, Su, Cafardi, Wiener, Tiwari, Kimberly, Davis: "The FCRL3-169CT promoter single-nucleotide polymorphism, which is associated with systemic lupus erythematosus in a Japanese population, predicts expression of receptor protein on CD19+ B cells." in: Arthritis and rheumatism, Vol. 60, Issue 11, pp. 3510-2, (2009) (PubMed).

  • 抗原

    FCRL3 (Fc Receptor-Like 3 (FCRL3))

    别名

    FCRL3

    背景

    This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains immunoreceptor-tyrosine activation motifs and immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain and may play a role in regulation of the immune system. Mutations in this gene have been associated with rheumatoid arthritis, autoimmune thyroid disease, and systemic lupus erythematosus.

    分子量

    80856

    NCBI登录号

    NP_443171

    UniProt

    Q96P31
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