FCRL3 抗体 (C-Term)
Quick Overview for FCRL3 抗体 (C-Term) (ABIN1881343)
抗原
See all FCRL3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 694-720, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This FCRL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 694-720 amino acids from the C-terminal region of human FCRL3.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Expression of the autoimmune susceptibility gene FcRL3 on human regulatory T cells is associated with dysfunction and high levels of programmed cell death-1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 7, pp. 3639-47, (2010) (PubMed).
: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, (2010) (PubMed).
: "[Study on the association of 3 SNPs of FcRL3 gene with Graves disease in Chongqing Han population]." in: Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, Vol. 26, Issue 6, pp. 681-5, (2009) (PubMed).
: "The FCRL3-169CT promoter single-nucleotide polymorphism, which is associated with systemic lupus erythematosus in a Japanese population, predicts expression of receptor protein on CD19+ B cells." in: Arthritis and rheumatism, Vol. 60, Issue 11, pp. 3510-2, (2009) (PubMed).
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: "Expression of the autoimmune susceptibility gene FcRL3 on human regulatory T cells is associated with dysfunction and high levels of programmed cell death-1." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 7, pp. 3639-47, (2010) (PubMed).
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- FCRL3 (Fc Receptor-Like 3 (FCRL3))
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别名
- FCRL3
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背景
- This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains immunoreceptor-tyrosine activation motifs and immunoreceptor-tyrosine inhibitory motifs in its cytoplasmic domain and may play a role in regulation of the immune system. Mutations in this gene have been associated with rheumatoid arthritis, autoimmune thyroid disease, and systemic lupus erythematosus.
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分子量
- 80856
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NCBI登录号
- NP_443171
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UniProt
- Q96P31
抗原
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