FAP 抗体 (N-Term)
Quick Overview for FAP 抗体 (N-Term) (ABIN1881337)
抗原
See all FAP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 15-41, N-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This Mouse Fap antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-41 amino acids from the N-terminal region of mouse Fap.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000. WB: 1:500. IHC-P: 1:100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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Immunotherapy targeting fibroblast activation protein inhibits tumor growth and increases survival in a murine colon cancer model." in: Cancer science, Vol. 101, Issue 11, pp. 2325-32, (2010) (PubMed).
: "Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice." in: The Journal of clinical investigation, Vol. 119, Issue 12, pp. 3613-25, (2009) (PubMed).
: "Elevation of seprase expression and promotion of an invasive phenotype by collagenous matrices in ovarian tumor cells." in: International journal of cancer. Journal international du cancer, Vol. 124, Issue 1, pp. 27-35, (2008) (PubMed).
: "
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Immunotherapy targeting fibroblast activation protein inhibits tumor growth and increases survival in a murine colon cancer model." in: Cancer science, Vol. 101, Issue 11, pp. 2325-32, (2010) (PubMed).
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- FAP (Fibroblast Activation Protein, alpha (FAP))
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别名
- Fap
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背景
- In association with DPP4 is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM (By similarity). May have a role in tissue remodeling during development and wound healing, and contribute to invasiveness in malignant cancers.
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分子量
- 87945
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NCBI登录号
- NP_032012
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UniProt
- P97321
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途径
- Tube Formation
抗原
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