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FAP 抗体 (N-Term)

This anti-FAP antibody is a 兔 多克隆 antibody detecting FAP in WB 和 IHC (p). Suitable for 小鼠. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN1881337
发货至: 中国

Quick Overview for FAP 抗体 (N-Term) (ABIN1881337)

抗原

See all FAP 抗体
FAP (Fibroblast Activation Protein, alpha (FAP))

适用

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小鼠

宿主

  • 70
  • 23

克隆类型

  • 65
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  • 2
多克隆

标记

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  • 1
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This FAP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB40867
  • 抗原表位

    • 16
    • 9
    • 6
    • 4
    • 4
    • 3
    • 3
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    AA 15-41, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This Mouse Fap antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-41 amino acids from the N-terminal region of mouse Fap.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000. WB: 1:500. IHC-P: 1:100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Wen, Wang, Ma, Li, Zhou, Mu, Leng, Shi, Li, Wei: "Immunotherapy targeting fibroblast activation protein inhibits tumor growth and increases survival in a murine colon cancer model." in: Cancer science, Vol. 101, Issue 11, pp. 2325-32, (2010) (PubMed).

    Santos, Jung, Aziz, Kissil, Puré: "Targeting fibroblast activation protein inhibits tumor stromagenesis and growth in mice." in: The Journal of clinical investigation, Vol. 119, Issue 12, pp. 3613-25, (2009) (PubMed).

    Kennedy, Dong, Chen, Chen: "Elevation of seprase expression and promotion of an invasive phenotype by collagenous matrices in ovarian tumor cells." in: International journal of cancer. Journal international du cancer, Vol. 124, Issue 1, pp. 27-35, (2008) (PubMed).

  • 抗原

    FAP (Fibroblast Activation Protein, alpha (FAP))

    别名

    Fap

    背景

    In association with DPP4 is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM (By similarity). May have a role in tissue remodeling during development and wound healing, and contribute to invasiveness in malignant cancers.

    分子量

    87945

    NCBI登录号

    NP_032012

    UniProt

    P97321

    途径

    Tube Formation
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