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EPC1 抗体 (AA 305-334)

This anti-EPC1 antibody is a 兔 多克隆 antibody detecting EPC1 in WB. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1881300
发货至: 中国

Quick Overview for EPC1 抗体 (AA 305-334) (ABIN1881300)

抗原

See all EPC1 抗体
EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))

适用

  • 18
  • 15
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  • 3
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  • 2
  • 1
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  • 1
人, 小鼠

宿主

  • 17
  • 3

克隆类型

  • 19
  • 1
多克隆

标记

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  • 1
  • 1
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This EPC1 antibody is un-conjugated

应用范围

  • 11
  • 4
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  • 1
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  • 1
Western Blotting (WB)
  • 抗原表位

    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 305-334

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This EPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-334 amino acids from the Central region of human EPC1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Deloukas, Earthrowl, Grafham, Rubenfield, French, Steward, Sims, Jones, Searle, Scott, Howe, Hunt, Andrews, Gilbert, Swarbreck, Ashurst, Taylor, Battles, Bird, Ainscough, Almeida, Ashwell, Ambrose et al.: "The DNA sequence and comparative analysis of human chromosome 10. ..." in: Nature, Vol. 429, Issue 6990, pp. 375-81, (2004) (PubMed).

    Shimono, Murakami, Hasegawa, Takahashi: "RET finger protein is a transcriptional repressor and interacts with enhancer of polycomb that has dual transcriptional functions." in: The Journal of biological chemistry, Vol. 275, Issue 50, pp. 39411-9, (2001) (PubMed).

  • 抗原

    EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))

    别名

    EPC1

    背景

    Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome -DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.

    分子量

    93463

    NCBI登录号

    NP_001258933, NP_001258948, NP_001269320, NP_079485

    UniProt

    Q9H2F5

    途径

    Regulation of Muscle Cell Differentiation
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