EPC1 抗体 (AA 305-334)
Quick Overview for EPC1 抗体 (AA 305-334) (ABIN1881300)
抗原
See all EPC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 305-334
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This EPC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-334 amino acids from the Central region of human EPC1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "The DNA sequence and comparative analysis of human chromosome 10. ..." in: Nature, Vol. 429, Issue 6990, pp. 375-81, (2004) (PubMed).
: "RET finger protein is a transcriptional repressor and interacts with enhancer of polycomb that has dual transcriptional functions." in: The Journal of biological chemistry, Vol. 275, Issue 50, pp. 39411-9, (2001) (PubMed).
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: "The DNA sequence and comparative analysis of human chromosome 10. ..." in: Nature, Vol. 429, Issue 6990, pp. 375-81, (2004) (PubMed).
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- EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))
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别名
- EPC1
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背景
- Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome -DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.
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分子量
- 93463
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NCBI登录号
- NP_001258933, NP_001258948, NP_001269320, NP_079485
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UniProt
- Q9H2F5
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途径
- Regulation of Muscle Cell Differentiation
抗原
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