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ENPP1 抗体 (N-Term)

There are 5+ publications for this product available. The 兔 多克隆 anti-ENPP1 antibody is suitable to detect ENPP1 in samples from 人. It has been validated for WB.
产品编号 ABIN1881296
发货至: 中国
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Quick Overview for ENPP1 抗体 (N-Term) (ABIN1881296)

抗原

See all ENPP1 抗体
ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))

适用

  • 40
  • 33
  • 11
  • 7
  • 4

宿主

  • 70
  • 6
  • 1

克隆类型

  • 73
  • 4
多克隆

标记

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  • 4
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  • 2
  • 1
  • 1
  • 1
  • 1
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  • 1
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  • 1
  • 1
  • 1
  • 1
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  • 1
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This ENPP1 antibody is un-conjugated

应用范围

  • 60
  • 25
  • 15
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  • 9
  • 6
  • 5
  • 5
  • 4
  • 2
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  • 1
Western Blotting (WB)

克隆位点

RB41733
  • 抗原表位

    • 15
    • 10
    • 8
    • 5
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    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
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    AA 6-34, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This ENPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-34 amino acids from the N-terminal region of human ENPP1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Ermakov, Rosenbaum, Malkin, Livshits: "Family-based study of association between ENPP1 genetic variants and craniofacial morphology." in: Annals of human biology, Vol. 37, Issue 6, pp. 754-66, (2010) (PubMed).

    Wang, Peng, Qu, Huang: "[Association and meta-analysis of ENPP1 K121Q with type 2 diabetes in Han Chinese.]." in: Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji, Vol. 32, Issue 8, pp. 808-16, (2010) (PubMed).

    Cruz, Valladares-Salgado, Garcia-Mena, Ross, Edwards, Angeles-Martinez, Ortega-Camarillo, de la Peña, Burguete-Garcia, Wacher-Rodarte, Ambriz, Rivera, Dartote, Peralta, Parra, Kumate: "Candidate gene association study conditioning on individual ancestry in patients with type 2 diabetes and metabolic syndrome from Mexico City." in: Diabetes/metabolism research and reviews, Vol. 26, Issue 4, pp. 261-70, (2010) (PubMed).

    Moehlecke, Kramer, Leitão, Krahe, Balbosco, Azevedo, Gross, Canani: "[ENPP1 K121Q polymorphism and ischemic heart disease in diabetic patients]." in: Arquivos brasileiros de cardiologia, Vol. 94, Issue 2, pp. 157-61, 168-73, 159-63, (2010) (PubMed).

    Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

  • 抗原

    ENPP1 (Ectonucleotide Pyrophosphatase/phosphodiesterase 1 (ENPP1))

    别名

    ENPP1

    背景

    This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance.

    分子量

    104924

    NCBI登录号

    NP_006199

    UniProt

    P22413

    途径

    Regulation of Carbohydrate Metabolic Process
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