EBP 抗体 (C-Term)
(3 references)Quick Overview for EBP 抗体 (C-Term) (ABIN1881278)
抗原
See all EBP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 201-230, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This EBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the C-terminal region of human EBP.
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亚型
- Ig Fraction
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anti-Emopamil Binding Protein (Sterol Isomerase) (EBP) (AA 2-230) antibody
EBP 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Emopamil Binding Protein (Sterol Isomerase) (EBP) (AA 1-30), (N-Term) antibodyEBP 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23728 unconjugated
anti-Emopamil Binding Protein (Sterol Isomerase) (EBP) (AA 77-126) antibodyEBP 适用: 人, 小鼠, 大鼠, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Emopamil Binding Protein (Sterol Isomerase) (EBP) (AA 50-150) antibodyEBP 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Two novel EBP mutations in Conradi-Hünermann-Happle syndrome." in: European journal of dermatology : EJD, Vol. 18, Issue 4, pp. 391-3, (2008) (PubMed).
: "Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations." in: Journal of lipid research, Vol. 49, Issue 12, pp. 2582-9, (2008) (PubMed).
: "Novel EBP gene mutations in Conradi-Hünermann-Happle syndrome." in: The British journal of dermatology, Vol. 157, Issue 6, pp. 1225-9, (2007) (PubMed).
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: "Two novel EBP mutations in Conradi-Hünermann-Happle syndrome." in: European journal of dermatology : EJD, Vol. 18, Issue 4, pp. 391-3, (2008) (PubMed).
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- EBP (Emopamil Binding Protein (Sterol Isomerase) (EBP))
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别名
- EBP
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背景
- The protein encoded by this gene is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. This protein shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of this protein is its high content of aromatic amino acid residues (>23 % ) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2, also known as Conradi-Hunermann syndrome).
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分子量
- 26353
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NCBI登录号
- NP_006570
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UniProt
- Q15125
抗原
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