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DHODH 抗体 (AA 166-194)

DHODH 适用: 人 WB 宿主: 兔 Polyclonal RB40540 unconjugated
产品编号 ABIN1881259
发货至: 中国
  • 抗原 See all DHODH 抗体
    DHODH (Dihydroorotate Dehydrogenase (DHODH))
    抗原表位
    • 9
    • 6
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 166-194
    适用
    • 43
    • 14
    • 13
    • 10
    • 9
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    宿主
    • 40
    • 3
    克隆类型
    • 41
    • 2
    多克隆
    标记
    • 29
    • 4
    • 3
    • 3
    • 2
    • 2
    This DHODH antibody is un-conjugated
    应用范围
    • 37
    • 27
    • 14
    • 6
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This DHODH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-194 amino acids from the Central region of human DHODH.
    克隆位点
    RB40540
    亚型
    Ig Fraction
    Top Product
    Discover our top product DHODH Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • Hail, Chen, Kepa, Bushman, Shearn: "Dihydroorotate dehydrogenase is required for N-(4-hydroxyphenyl)retinamide-induced reactive oxygen species production and apoptosis." in: Free radical biology & medicine, Vol. 49, Issue 1, pp. 109-16, (2010) (PubMed).

    Ng, Buckingham, Lee, Bigham, Tabor, Dent, Huff, Shannon, Jabs, Nickerson, Shendure, Bamshad: "Exome sequencing identifies the cause of a mendelian disorder." in: Nature genetics, Vol. 42, Issue 1, pp. 30-5, (2009) (PubMed).

    Grabar, Rozman, Logar, Praprotnik, Dolzan: "Dihydroorotate dehydrogenase polymorphism influences the toxicity of leflunomide treatment in patients with rheumatoid arthritis." in: Annals of the rheumatic diseases, Vol. 68, Issue 8, pp. 1367-8, (2009) (PubMed).

    Pawlik, Herczynska, Kurzawski, Safranow, Dziedziejko, Drozdzik: "The effect of exon (19C>A) dihydroorotate dehydrogenase gene polymorphism on rheumatoid arthritis treatment with leflunomide." in: Pharmacogenomics, Vol. 10, Issue 2, pp. 303-9, (2009) (PubMed).

  • 抗原
    DHODH (Dihydroorotate Dehydrogenase (DHODH))
    别名
    DHODH (DHODH 产品)
    别名
    DHOdehase antibody, POADS antibody, URA1 antibody, 2810417D19Rik antibody, AI834883 antibody, DDBDRAFT_0167009 antibody, DDBDRAFT_0185217 antibody, DDB_0167009 antibody, DDB_0185217 antibody, DHOD antibody, DHODase antibody, XFHB_12025 antibody, dhodh antibody, dihydroorotate dehydrogenase (quinone) antibody, dihydroorotate dehydrogenase antibody, dihydroorotate dehydrogenase (quinone) L homeolog antibody, DHODH antibody, Dhodh antibody, pyrD antibody, pyr4 antibody, Mrub_0263 antibody, Arnit_2124 antibody, Trad_2703 antibody, Ftrac_1484 antibody, Ndas_0799 antibody, Mesil_1876 antibody, Slip_0841 antibody, Spirs_1436 antibody, XFHB_RS12780 antibody, dhodh.L antibody
    背景
    The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane.
    分子量
    42867
    NCBI登录号
    NP_001352
    UniProt
    Q02127
    途径
    Ribonucleoside Biosynthetic Process, Protein targeting to Nucleus
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