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DHODH 抗体 (AA 166-194)

Cited in 4+ publications. This 兔 多克隆 anti-DHODH antibody (Clone RB40540) specifically detects DHODH in WB. The antibody is reactive with 人 samples.
产品编号 ABIN1881259
发货至: 中国
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Quick Overview for DHODH 抗体 (AA 166-194) (ABIN1881259)

抗原

See all DHODH 抗体
DHODH (Dihydroorotate Dehydrogenase (DHODH))

适用

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宿主

  • 39
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克隆类型

  • 40
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多克隆

标记

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This DHODH antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB40540
  • 抗原表位

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    AA 166-194

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This DHODH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 166-194 amino acids from the Central region of human DHODH.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Hail, Chen, Kepa, Bushman, Shearn: "Dihydroorotate dehydrogenase is required for N-(4-hydroxyphenyl)retinamide-induced reactive oxygen species production and apoptosis." in: Free radical biology & medicine, Vol. 49, Issue 1, pp. 109-16, (2010) (PubMed).

    Ng, Buckingham, Lee, Bigham, Tabor, Dent, Huff, Shannon, Jabs, Nickerson, Shendure, Bamshad: "Exome sequencing identifies the cause of a mendelian disorder." in: Nature genetics, Vol. 42, Issue 1, pp. 30-5, (2009) (PubMed).

    Grabar, Rozman, Logar, Praprotnik, Dolzan: "Dihydroorotate dehydrogenase polymorphism influences the toxicity of leflunomide treatment in patients with rheumatoid arthritis." in: Annals of the rheumatic diseases, Vol. 68, Issue 8, pp. 1367-8, (2009) (PubMed).

    Pawlik, Herczynska, Kurzawski, Safranow, Dziedziejko, Drozdzik: "The effect of exon (19C>A) dihydroorotate dehydrogenase gene polymorphism on rheumatoid arthritis treatment with leflunomide." in: Pharmacogenomics, Vol. 10, Issue 2, pp. 303-9, (2009) (PubMed).

  • 抗原

    DHODH (Dihydroorotate Dehydrogenase (DHODH))

    别名

    DHODH

    背景

    The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane.

    分子量

    42867

    NCBI登录号

    NP_001352

    UniProt

    Q02127

    途径

    Ribonucleoside Biosynthetic Process, Protein targeting to Nucleus
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