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CXCR4 抗体 (N-Term)

This anti-CXCR4 antibody is a 兔 多克隆 antibody detecting CXCR4 in WB. Suitable for 人. This Primary Antibody has been cited in 6+ publications.
产品编号 ABIN1881244
发货至: 中国

Quick Overview for CXCR4 抗体 (N-Term) (ABIN1881244)

抗原

See all CXCR4 抗体
CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

适用

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宿主

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克隆类型

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多克隆

标记

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This CXCR4 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB41207
  • 抗原表位

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    AA 50-79, N-Term

    预测反应

    B, Pr, M, Pig, Rat, Sh

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This CXCR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-79 amino acids from the N-terminal region of human CXCR4.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Zhou, Liu, Li, Zhang, Wang, Lan, Shi, Li, Ju: "Migration ability and Toll-like receptor expression of human mesenchymal stem cells improves significantly after three-dimensional culture." in: Biochemical and biophysical research communications, Vol. 491, Issue 2, pp. 323-328, (2017) (PubMed).

    Zhu, Hong, Tripathi, Sehdev, Belkhiri, El-Rifai: "Regulation of CXCR4-mediated invasion by DARPP-32 in gastric cancer cells." in: Molecular cancer research : MCR, Vol. 11, Issue 1, pp. 86-94, (2013) (PubMed).

    Hammad, Kuang, Yan, Allen, Dupré: "Na+/H+ exchanger regulatory factor-1 is involved in chemokine receptor homodimer CCR5 internalization and signal transduction but does not affect CXCR4 homodimer or CXCR4-CCR5 heterodimer." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34653-64, (2010) (PubMed).

    Wang, Guilpain, Chong, Chouzenoux, Guillevin, Du, Zhou, Lin, Fairhurst, Boudreaux, Roux, Wakeland, Davis, Batteux, Mohan: "Dysregulated expression of CXCR4/CXCL12 in subsets of patients with systemic lupus erythematosus." in: Arthritis and rheumatism, Vol. 62, Issue 11, pp. 3436-46, (2010) (PubMed).

    Cheng, Zhou, Wu, Boriboun, Thorne, Liu, Xiang, Zeng, Tanaka, Tang, Kishore, Tomasson, Miller, Losordo, Qin: "CXCR4-mediated bone marrow progenitor cell maintenance and mobilization are modulated by c-kit activity." in: Circulation research, Vol. 107, Issue 9, pp. 1083-93, (2010) (PubMed).

    Sanematsu, Hirashima, Laurin, Takii, Nishikimi, Kitajima, Ding, Noda, Murata, Tanaka, Masuko, Suda, Meno, C��té, Nagasawa, Fukui: "DOCK180 is a Rac activator that regulates cardiovascular development by acting downstream of CXCR4." in: Circulation research, Vol. 107, Issue 9, pp. 1102-5, (2010) (PubMed).

  • 抗原

    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

    别名

    CXCR4

    背景

    This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].

    分子量

    39746

    NCBI登录号

    NP_001008540, NP_003458

    UniProt

    P61073

    途径

    Regulation of Cell Size, CXCR4-mediated Signaling Events
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