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CREB3 抗体 (N-Term)

This anti-CREB3 antibody is a 兔 多克隆 antibody detecting CREB3 in WB. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN1881228
发货至: 中国

Quick Overview for CREB3 抗体 (N-Term) (ABIN1881228)

抗原

See all CREB3 抗体
CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))

适用

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宿主

  • 32
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克隆类型

  • 33
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多克隆

标记

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This CREB3 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB42213
  • 抗原表位

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    AA 66-94, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This CREB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human CREB3.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Kim, Choi, Choi, Kang, Kim, Lee, Lee, Lee, Kim, Jun, Jeong, Yoon: "HDAC3 selectively represses CREB3-mediated transcription and migration of metastatic breast cancer cells." in: Cellular and molecular life sciences : CMLS, Vol. 67, Issue 20, pp. 3499-510, (2010) (PubMed).

    Audas, Li, Liang, Lu: "A novel protein, Luman/CREB3 recruitment factor, inhibits Luman activation of the unfolded protein response." in: Molecular and cellular biology, Vol. 28, Issue 12, pp. 3952-66, (2008) (PubMed).

  • 抗原

    CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))

    别名

    CREB3

    背景

    This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-response element and regulates cell proliferation. The protein interacts with host cell factor C1, which also associates with the herpes simplex virus (HSV) protein VP16 that induces transcription of HSV immediate-early genes. This protein and VP16 both bind to the same site on host cell factor C1. It is thought that the interaction between this protein and host cell factor C1 plays a role in the establishment of latency during HSV infection. This protein also plays a role in leukocyte migration, tumor suppression, and endoplasmic reticulum stress-associated protein degradation. Additional transcript variants have been identified, but their biological validity has not been determined.

    分子量

    41379

    NCBI登录号

    NP_006359

    UniProt

    O43889

    途径

    Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Maintenance of Protein Location, Unfolded Protein Response
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