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COL10A1 抗体 (N-Term)

This anti-COL10A1 antibody is a 兔 多克隆 antibody detecting COL10A1 in WB. Suitable for 人. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN1881220
发货至: 中国

Quick Overview for COL10A1 抗体 (N-Term) (ABIN1881220)

抗原

See all COL10A1 抗体
COL10A1 (Collagen, Type X, alpha 1 (COL10A1))

适用

  • 22
  • 4
  • 3

宿主

  • 22

克隆类型

  • 20
  • 2
多克隆

标记

  • 10
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This COL10A1 antibody is un-conjugated

应用范围

  • 14
  • 13
  • 5
  • 1
Western Blotting (WB)

克隆位点

RB40406
  • 抗原表位

    • 6
    • 3
    • 2
    • 1
    • 1
    AA 29-58, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This COL10A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human COL10A1.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Mäkitie, Susic, Cole: "Early-onset metaphyseal chondrodysplasia type Schmid associated with a COL10A1 frame-shift mutation and impaired trimerization of wild-type α1(X) protein chains." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Vol. 28, Issue 11, pp. 1497-501, (2010) (PubMed).

    Wang, Qiu, Ma, Xia, Zhu, Zhu: "Expression of Runx2 and type X collagen in vertebral growth plate of patients with adolescent idiopathic scoliosis." in: Connective tissue research, Vol. 51, Issue 3, pp. 188-96, (2010) (PubMed).

    Videman, Saarela, Kaprio, Näkki, Levälahti, Gill, Peltonen, Battié: "Associations of 25 structural, degradative, and inflammatory candidate genes with lumbar disc desiccation, bulging, and height narrowing." in: Arthritis and rheumatism, Vol. 60, Issue 2, pp. 470-81, (2009) (PubMed).

    Higashikawa, Saito, Ikeda, Kamekura, Kawamura, Kan, Oshima, Ohba, Ogata, Takeshita, Nakamura, Chung, Kawaguchi: "Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type X collagen gene." in: Arthritis and rheumatism, Vol. 60, Issue 1, pp. 166-78, (2009) (PubMed).

    Zimmermann, Boeuf, Dickhut, Boehmer, Olek, Richter: "Correlation of COL10A1 induction during chondrogenesis of mesenchymal stem cells with demethylation of two CpG sites in the COL10A1 promoter." in: Arthritis and rheumatism, Vol. 58, Issue 9, pp. 2743-53, (2008) (PubMed).

  • 抗原

    COL10A1 (Collagen, Type X, alpha 1 (COL10A1))

    别名

    COL10A1

    背景

    This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD).

    分子量

    66158

    NCBI登录号

    NP_000484

    UniProt

    Q03692
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