COL10A1 抗体 (N-Term)
Quick Overview for COL10A1 抗体 (N-Term) (ABIN1881220)
抗原
See all COL10A1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 29-58, N-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This COL10A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-58 amino acids from the N-terminal region of human COL10A1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Early-onset metaphyseal chondrodysplasia type Schmid associated with a COL10A1 frame-shift mutation and impaired trimerization of wild-type α1(X) protein chains." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Vol. 28, Issue 11, pp. 1497-501, (2010) (PubMed).
: "Expression of Runx2 and type X collagen in vertebral growth plate of patients with adolescent idiopathic scoliosis." in: Connective tissue research, Vol. 51, Issue 3, pp. 188-96, (2010) (PubMed).
: "Associations of 25 structural, degradative, and inflammatory candidate genes with lumbar disc desiccation, bulging, and height narrowing." in: Arthritis and rheumatism, Vol. 60, Issue 2, pp. 470-81, (2009) (PubMed).
: "Identification of the core element responsive to runt-related transcription factor 2 in the promoter of human type X collagen gene." in: Arthritis and rheumatism, Vol. 60, Issue 1, pp. 166-78, (2009) (PubMed).
: "Correlation of COL10A1 induction during chondrogenesis of mesenchymal stem cells with demethylation of two CpG sites in the COL10A1 promoter." in: Arthritis and rheumatism, Vol. 58, Issue 9, pp. 2743-53, (2008) (PubMed).
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: "Early-onset metaphyseal chondrodysplasia type Schmid associated with a COL10A1 frame-shift mutation and impaired trimerization of wild-type α1(X) protein chains." in: Journal of orthopaedic research : official publication of the Orthopaedic Research Society, Vol. 28, Issue 11, pp. 1497-501, (2010) (PubMed).
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- COL10A1 (Collagen, Type X, alpha 1 (COL10A1))
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别名
- COL10A1
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背景
- This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD).
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分子量
- 66158
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NCBI登录号
- NP_000484
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UniProt
- Q03692
抗原
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