Cyclin B1 抗体 (pSer35)
Quick Overview for Cyclin B1 抗体 (pSer35) (ABIN1881155)
抗原
See all Cyclin B1 (CCNB1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pSer35
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This CCNB1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S35 of human CCNB1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1100. DB: 1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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Restoration of the tumor suppressor p53 by downregulating cyclin B1 in human papillomavirus 16/18-infected cancer cells." in: Oncogene, Vol. 29, Issue 41, pp. 5591-603, (2010) (PubMed).
: "The APC/C recruits cyclin B1-Cdk1-Cks in prometaphase before D box recognition to control mitotic exit." in: The Journal of cell biology, Vol. 190, Issue 4, pp. 587-602, (2010) (PubMed).
: "Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest." in: The EMBO journal, Vol. 29, Issue 14, pp. 2407-20, (2010) (PubMed).
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Restoration of the tumor suppressor p53 by downregulating cyclin B1 in human papillomavirus 16/18-infected cancer cells." in: Oncogene, Vol. 29, Issue 41, pp. 5591-603, (2010) (PubMed).
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- Cyclin B1 (CCNB1)
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别名
- CCNB1
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背景
- The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq].
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分子量
- 48337
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NCBI登录号
- NP_114172
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UniProt
- P14635
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途径
- Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase
抗原
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