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BLMH 抗体 (AA 212-242)

There are 2+ publications for this product available. The 兔 多克隆 anti-BLMH antibody is suitable to detect BLMH in samples from 人, 大鼠 和 小鼠. It has been validated for WB 和 IHC (p).
产品编号 ABIN1881113
发货至: 中国
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Quick Overview for BLMH 抗体 (AA 212-242) (ABIN1881113)

抗原

See all BLMH 抗体
BLMH (Bleomycin Hydrolase (BLMH))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

  • 50
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多克隆

标记

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This BLMH antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 212-242

    预测反应

    Rb

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This BLMH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-242 amino acids from the Central region of human BLMH.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Ferrando, Velasco, Campo, Lopez-Otin: "Cloning and expression analysis of human bleomycin hydrolase, a cysteine proteinase involved in chemotherapy resistance." in: Cancer research, Vol. 56, Issue 8, pp. 1746-50, (1996) (PubMed).

    Brömme, Rossi, Smeekens, Anderson, Payan: "Human bleomycin hydrolase: molecular cloning, sequencing, functional expression, and enzymatic characterization." in: Biochemistry, Vol. 35, Issue 21, pp. 6706-14, (1996) (PubMed).

  • 抗原

    BLMH (Bleomycin Hydrolase (BLMH))

    别名

    BLMH

    背景

    The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity (By similarity).

    分子量

    52562

    NCBI登录号

    NP_000377

    UniProt

    Q13867
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