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BCL9L 抗体 (N-Term)

Cited in 4+ publications. This anti-BCL9L antibody is a 兔 多克隆 antibody detecting BCL9L in WB. Suitable for 人.
产品编号 ABIN1881110
发货至: 中国
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Quick Overview for BCL9L 抗体 (N-Term) (ABIN1881110)

抗原

See all BCL9L 抗体
BCL9L (B-Cell CLL/lymphoma 9-Like (BCL9L))

适用

  • 16
  • 4
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宿主

  • 14
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克隆类型

  • 14
  • 2
多克隆

标记

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  • 1
  • 1
This BCL9L antibody is un-conjugated

应用范围

  • 14
  • 13
  • 2
  • 2
  • 2
  • 2
  • 1
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  • 1
Western Blotting (WB)

克隆位点

RB41624
  • 抗原表位

    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 147-176, N-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This BCL9L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-176 amino acids from the N-terminal region of human BCL9L.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Miller, Rutherford, Johnson, Fiedler, Bienz: "Allosteric remodelling of the histone H3 binding pocket in the Pygo2 PHD finger triggered by its binding to the B9L/BCL9 co-factor." in: Journal of molecular biology, Vol. 401, Issue 5, pp. 969-84, (2010) (PubMed).

    Fritzmann, Morkel, Besser, Budczies, Kosel, Brembeck, Stein, Fichtner, Schlag, Birchmeier: "A colorectal cancer expression profile that includes transforming growth factor beta inhibitor BAMBI predicts metastatic potential." in: Gastroenterology, Vol. 137, Issue 1, pp. 165-75, (2009) (PubMed).

    Sampietro, Dahlberg, Cho, Hinds, Kimelman, Xu: "Crystal structure of a beta-catenin/BCL9/Tcf4 complex." in: Molecular cell, Vol. 24, Issue 2, pp. 293-300, (2006) (PubMed).

    Brembeck, Schwarz-Romond, Bakkers, Wilhelm, Hammerschmidt, Birchmeier: "Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions." in: Genes & development, Vol. 18, Issue 18, pp. 2225-30, (2004) (PubMed).

  • 抗原

    BCL9L (B-Cell CLL/lymphoma 9-Like (BCL9L))

    别名

    BCL9L

    背景

    Transcriptional regulator that acts as an activator. Promotes beta-catenin transcriptional activity. Plays a role in tumorigenesis. Enhances the neoplastic transforming activity of CTNNB1 (By similarity).

    分子量

    157129

    NCBI登录号

    NP_872363

    UniProt

    Q86UU0

    途径

    Stem Cell Maintenance
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