Angiomotin 抗体 (pTyr599)
Quick Overview for Angiomotin 抗体 (pTyr599) (ABIN1881054)
抗原
See all Angiomotin (AMOT) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- pTyr599
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预测反应
- M
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This AMOT Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y599 of human AMOT.
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亚型
- Ig Fraction
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应用备注
- DB: 1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Amot recognizes a juxtanuclear endocytic recycling compartment via a novel lipid binding domain." in: The Journal of biological chemistry, Vol. 285, Issue 16, pp. 12308-20, (2010) (PubMed).
: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).
: "Human angiomotin-like 1 associates with an angiomotin protein complex through its coiled-coil domain and induces the remodeling of the actin cytoskeleton." in: Cell motility and the cytoskeleton, Vol. 66, Issue 9, pp. 754-68, (2009) (PubMed).
: "Angiomotin-like protein 1 controls endothelial polarity and junction stability during sprouting angiogenesis." in: Circulation research, Vol. 105, Issue 3, pp. 260-70, (2009) (PubMed).
: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).
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: "Amot recognizes a juxtanuclear endocytic recycling compartment via a novel lipid binding domain." in: The Journal of biological chemistry, Vol. 285, Issue 16, pp. 12308-20, (2010) (PubMed).
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- Angiomotin (AMOT)
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别名
- AMOT
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背景
- This gene belongs to the motin family of angiostatin binding proteins characterized by conserved coiled-coil domains and C-terminal PDZ binding motifs. The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels. Alternative splicing results in multiple transcript variants encoding different isoforms.
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分子量
- 118085
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NCBI登录号
- NP_001106962, NP_573572
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UniProt
- Q4VCS5
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途径
- Cell-Cell Junction Organization, Regulation of Cell Size
抗原
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