电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

AKTIP 抗体 (C-Term)

This anti-AKTIP antibody is a 兔 多克隆 antibody detecting AKTIP in WB. Suitable for 人. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN1881052
发货至: 中国

Quick Overview for AKTIP 抗体 (C-Term) (ABIN1881052)

抗原

See all AKTIP 抗体
AKTIP (AKT Interacting Protein (AKTIP))

适用

  • 31
  • 30
  • 24
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1

宿主

  • 54
  • 6

克隆类型

  • 57
  • 3
多克隆

标记

  • 17
  • 5
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This AKTIP antibody is un-conjugated

应用范围

  • 48
  • 26
  • 26
  • 22
  • 6
  • 6
  • 3
  • 2
  • 1
Western Blotting (WB)

克隆位点

RB38675
  • 抗原表位

    • 30
    • 12
    • 7
    • 2
    • 2
    • 1
    • 1
    AA 262-288, C-Term

    预测反应

    C, Pr, M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This AKTIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-288 amino acids from the C-terminal region of human AKTIP.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Quaye, Dafou, Ramus, Song, Gentry-Maharaj, Maharaj, Notaridou, Hogdall, Kjaer, Christensen, Hogdall, Easton, Jacobs, Menon, Pharoah, Gayther: "Functional complementation studies identify candidate genes and common genetic variants associated with ovarian cancer survival." in: Human molecular genetics, Vol. 18, Issue 10, pp. 1869-78, (2009) (PubMed).

    Xu, Sowa, Chen, Li, Gygi, Harper: "An FTS/Hook/p107(FHIP) complex interacts with and promotes endosomal clustering by the homotypic vacuolar protein sorting complex." in: Molecular biology of the cell, Vol. 19, Issue 12, pp. 5059-71, (2008) (PubMed).

    Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, (2007) (PubMed).

  • 抗原

    AKTIP (AKT Interacting Protein (AKTIP))

    别名

    AKTIP

    背景

    The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein.

    分子量

    33128

    NCBI登录号

    NP_001012398, NP_071921

    UniProt

    Q9H8T0
You are here:
Chat with us!