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ADRA1B 抗体 (C-Term)

This anti-ADRA1B antibody is a 兔 多克隆 antibody detecting ADRA1B in WB. Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN1881048
发货至: 中国

Quick Overview for ADRA1B 抗体 (C-Term) (ABIN1881048)

抗原

See all ADRA1B 抗体
ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

适用

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宿主

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克隆类型

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多克隆

标记

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This ADRA1B antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB41818
  • 抗原表位

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    AA 380-409, C-Term

    预测反应

    M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This ADRA1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 380-409 amino acids from the C-terminal region of human ADRA1B.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: "Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study." in: Diabetes Care, Vol. 33, Issue 10, pp. 2250-3, (2010) (PubMed).

    Jensen, Swigart, De Marco, Hoopes, Simpson: "{alpha}1-Adrenergic receptor subtypes in nonfailing and failing human myocardium." in: Circulation. Heart failure, Vol. 2, Issue 6, pp. 654-63, (2009) (PubMed).

    Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

    Hanna, Kruskal, Ezekowitz, Bloom, Collier: "Role of macrophage oxidative burst in the action of anthrax lethal toxin." in: Molecular medicine (Cambridge, Mass.), Vol. 1, Issue 1, pp. 7-18, (1996) (PubMed).

  • 抗原

    ADRA1B (Adrenergic, alpha-1B-, Receptor (ADRA1B))

    别名

    ADRA1B

    背景

    Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.

    分子量

    56836

    NCBI登录号

    NP_000670

    UniProt

    P35368

    途径

    AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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