CD51/CD61 抗体
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北京 101111
Quick Overview for CD51/CD61 抗体 (ABIN187672)
抗原
See all CD51/CD61 (ITGAV/ITGB3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes 110/90 kDa antigen known as the alpha chain of the vitronectin receptor (VNR). Clone 23C6 reacts with osteoclasts, placenta, melanoma cell lines, some epithelia cells. It reacts weakly with platelets. Clone 23C6 recognises the intact complex formed between the CD51 and CD61 molecules (av and b3 integrins). This complex binds vitronectin at the RGD sequence and can also bind von Willebrand factor, fibrinogen, thrombospondin, fibronectin, osteopontin and collagen. Species Reactivity: Human and chicken. Does not cross react with porcine, lapine or bovine tissues.
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免疫原
- Human osteoclastoma tissue
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亚型
- IgG1
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应用备注
- Flow Cytometry: Working dilution of 1:40 -1:80. Recommended second antibodies: FITC-conjugated F(ab')2 rabbit anti-mouse IgG Immunohistochemistry -Frozen sections: Working dilution of 1:50-1:100. Clone 23C6 shows no reactivity on fixed tissues. Immunoprecipitation The optimal dilution for a specific application should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Product: 200 µg purified IgG at approximately 1 mg/mL in PBS at pH 7.4 with 0.09% sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- CD51/CD61 (ITGAV/ITGB3) (Integrin alpha V, Integrin beta 3 (ITGAV/ITGB3))
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别名
- CD51/CD61 Complex
抗原
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