Recognizes 110/90 kDa antigen known as the alpha chain of the vitronectin receptor (VNR). Clone 23C6 reacts with osteoclasts, placenta, melanoma cell lines, some epithelia cells. It reacts weakly with platelets. Clone 23C6 recognises the intact complex formed between the CD51 and CD61 molecules (av and b3 integrins). This complex binds vitronectin at the RGD sequence and can also bind von Willebrand factor, fibrinogen, thrombospondin, fibronectin, osteopontin and collagen. Species Reactivity: Human and chicken. Does not cross react with porcine, lapine or bovine tissues.
ITGAV/ITGB3
适用: 人, 小鼠, 大鼠
FACS, WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
AbBy Fluor® 594
应用备注
Flow Cytometry: Working dilution of 1:40 -1:80. Recommended second antibodies: FITC-conjugated F(ab')2 rabbit anti-mouse IgG Immunohistochemistry -Frozen sections: Working dilution of 1:50-1:100. Clone 23C6 shows no reactivity on fixed tissues. Immunoprecipitation The optimal dilution for a specific application should be determined by the researcher.
限制
仅限研究用
状态
Liquid
缓冲液
Product: 200 µg purified IgG at approximately 1 mg/mL in PBS at pH 7.4 with 0.09% sodium azide.
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.