BMF 抗体
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北京 101111
Quick Overview for BMF 抗体 (ABIN187548)
抗原
See all BMF 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes human and mouse Bmf. Species Reactivity: Human and mouse. Others not tested.
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免疫原
- Recombinant mouse Bmf fused to glutathione-S-transferase (GST).
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亚型
- IgG1
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anti-Bcl2 Modifying Factor (BMF) (AA 1-181) antibody
BMF 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bcl2 Modifying Factor (BMF) (AA 112-126), (AA 13-27) antibodyBMF 适用: 小鼠, 大鼠 WB, IHC, ELISA, FACS, IP, ICC 宿主: 大鼠 Monoclonal 17A9 unconjugated
anti-Bcl2 Modifying Factor (BMF) (AA 1-184) antibodyBMF 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Bcl2 Modifying Factor (BMF) (AA 115-150) antibodyBMF 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB00594 unconjugated
anti-Bcl2 Modifying Factor (BMF) (BH3 Domain) antibodyBMF 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bcl2 Modifying Factor (BMF) (N-Term) antibodyBMF 适用: 人, 小鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-Bcl2 Modifying Factor (BMF) (AA 130-150), (BH3 Domain) antibodyBMF 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot: Use at 0.5-1.0 µg/mL Flow cytometry: Use at 1-10 µg/mL (1:100- 1:1,000 dilution) Immunoprecipitation: Use at 2-5 µg/mL The optimal dilution for a specific application should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 100 µg of protein G purified antibody in PBS containing 0.02% sodium azide. Concentration is 1 mg/mL.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- BMF (Bcl2 Modifying Factor (BMF))
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别名
- BMF
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背景
- Bmf is a novel BH3-only protein that was discovered in a yeast 2-hybrid library screen with Mcl-1 (a pro-survival member of the Bcl-2 family) as the target molecule. Biochemical experiments demonstrated that Bmf binds to Bcl-2 and all of its pro-survival homologs through its BH3 domain. Co-immunoprecipitation of Bmf and Bcl-2 can be detected in cells that express both proteins at physiological levels. Bmf promotes apoptosis by blocking the pro-survival activity of Bcl-2 and its homologs. In healthy cells, Bmf is sequestered to the actin cytoskeleton, via dynein light chain 2 (DLC2), allowing it to translocate and bind Bcl-2 and its homologs.
抗原
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