ABCA1 抗体
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北京 101111
Quick Overview for ABCA1 抗体 (ABIN187475)
抗原
See all ABCA1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) are associated with Tangier disease (TD). TD is an autosomal recessive disorder resulting from an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and disorders in cellular lipid trafficking. It is expressed on the plasma membrane and the Golgi complex and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI. Species Human. Other species not tested.
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免疫原
- Peptide corresponding to amino acids 1800-2260.
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亚型
- IgG1
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应用备注
- Immunohistochemistry Western blot ELISA Immunoprecipitation The optimal dilution for a specific application should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 100 µg of antibody at 1 mg/mL in PBS, pH 7.4, with 0.5% sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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- ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))
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别名
- ABCA1
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途径
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism
抗原
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