MVP 抗体
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北京 101111
Quick Overview for MVP 抗体 (ABIN187372)
抗原
See all MVP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Species Reactivity: Human, other species not tested.
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免疫原
- A BALB/c mouse was immunized with 5 µg of affinity purified nuclear extract proteins. Spleen cells were fused with equal number of Sp0Ag-14 myeloma cells. Cells whose supernatant showed a positive signal for a 104 kDa band were selected and cloned by limited dilution.
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亚型
- IgM
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应用备注
- Clone 1027 can be applied for the detection of MVP/LRP in a large number of eukaryotic cells including the MCF-7 and Hela tumor cell lines. Immunohistochemistry: Frozen sections Western blot The optimal dilution for a specific application should be determined by the researcher.
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限制
- 仅限研究用
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状态
- Lyophilized
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缓冲液
- 100 µg purified, lyophilized.
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储存条件
- 4 °C
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- MVP (Major Vault Protein (MVP))
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别名
- Major Vault Protein
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背景
- The mAb clone 1027 is specific for a 104 kDa protein. The antibody is one of four mAb which recognize different epitopes of the protein. This 104 kDa protein is the major vault protein (MVP) also described as the lung resistance protein (LRP) and has been shown to interact with the estrogen receptor. The protein is part of a very large vault ribonucleoprotein complex present in all eukaryotic cells and its structure and protein composition is highly conserved. Because of the size, shape, protein and RNA composition of this complex the particles are different from other ribonucleoproteins. The mAb is especially applicable for studying the association of estrgen receptor with vaults and the study of the mechanism of action of estrogenic hormones.
抗原
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