MVP 抗体
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北京 101111
Quick Overview for MVP 抗体 (ABIN187371)
抗原
See all MVP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The mAb 1011 is specific for a 104 kDa protein. This mAb is one of four mAb which recognize different epitopes of the protein. This 104 kDa protein is the major vault protein and has shown to interact with the estrogen receptor. The protein is part of a very large vault ribonucleoprotein complex present in all eukaryotic cells and its structure and protein composition is highly conserved. Because of the size, shape, and protein and RNA composition of this complex the particles are different from other ribonucleoproteins. Species Reactivity: Human, others not tested.
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免疫原
- Recombinant human MVPA BALB/c mouse was immunized with 5 µg of affinity purified nuclear extract proteins. Spleen cells were fused with equal number of Sp0Ag-14 myeloma cells. Cells whose supernatant showed a positive signal for a 104 kDa band were selected and cloned by limited dilution.
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亚型
- IgG1
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应用备注
- The mAb 1011 can be applied for the detection of the major vault protein in a large number of eukaryotic cells including the MCF-7 and Hela tumor cell lines. The mAb are especially applicable to study the association of estrogen receptor with vaults and the study of the mechanism of action of estrogenic hormones. Western blot Immunohistology (Frozen) The optimal dilution for a specific application should be determined by the researcher.
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限制
- 仅限研究用
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缓冲液
- 100 µg purified antibody.
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储存条件
- 4 °C
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- MVP (Major Vault Protein (MVP))
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别名
- Major Vault Protein
抗原
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