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Desmoglein 3 抗体

The 小鼠 单克隆 anti-Desmoglein 3 antibody is suitable to detect Desmoglein 3 in samples from 人. It has been validated for WB, IF, IP 和 IHC (p).
产品编号 ABIN187349
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Desmoglein 3 抗体 (ABIN187349)

抗原

See all Desmoglein 3 (DSG3) 抗体
Desmoglein 3 (DSG3)

适用

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宿主

  • 81
  • 76
小鼠

克隆类型

  • 90
  • 65
  • 2
单克隆

标记

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  • 1
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  • 1
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This Desmoglein 3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

5G11
  • 特异性

    Reacts with the 140 kDa desmoglein 3 protein. Does not cross-react with desmoglein 1 or desmoglein 2. The antibody does not inhibit biological activity of desmoglein 3. Species Reactivity: Human. Others not tested.

    过滤

    0.2 μm filtered

    亚型

    IgG1
  • 应用备注

    Immunofluorescence: Use at a 1:10 dilution Immunohistochemistry (paraffin embedded sections) Immunoprecipitation Western blot: Use at a 1:10 dilution The optimal dilution for a specific application should be determined by the researcher.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    1 mL at 100 µg/mL of 0.2 µm filtered antibody solution in PBS containing 0.1% protein stabilizer and 0.02% sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • 抗原

    Desmoglein 3 (DSG3)

    别名

    Desmoglein-3

    背景

    Desmoglein 3 is a member of the desmosomal cadherin family that comprise the desmogleins and desmocollins. Desmosomes are cell-cell junctions in most epithelial cells and serve to link the intermediate filament cytoskeletons of adjacent cells. Within the desmosome the extracellular domain of desmoglein is essential for calcium dependent heterophilic binding to the desmocollins, whereas the intracellular domain is essential for binding to the desmosomal plaque protein, plakoglobin. Desmoglein 3 is synthesized in both the basal and the lower suprabasal compartments.
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