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Transgelin 抗体 (C-Term)

This anti-Transgelin antibody is a 山羊 多克隆 antibody detecting Transgelin in WB, ELISA 和 IHC. Suitable for 人. This Primary Antibody has been cited in 4+ publications.
产品编号 ABIN185188
发货至: 中国

Quick Overview for Transgelin 抗体 (C-Term) (ABIN185188)

抗原

See all Transgelin (TAGLN) 抗体
Transgelin (TAGLN)

适用

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宿主

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山羊

克隆类型

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多克隆

标记

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This Transgelin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

质量等级

Verified
  • 抗原表位

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    C-Term

    原理

    SM22 Alpha / Transgelin

    序列

    MTGYGRPRQI IS

    特异性

    NP_003177.2 and NP_001001522.1 represent identical protein. The transgelin protein is found in fibroblasts and smooth muscle and is known as a transformation or shape change protein that is involved with actin cross-linking. Transgelin is one of the earli

    交叉反应

    Cow, 犬, 人, 小鼠, 大鼠

    纯化方法

    Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

    免疫原

    C-MTGYGRPRQIIS

    亚型

    IgG
  • 应用备注

    Immunohistochemistry: Paraffin embedded Human Prostate. Recommended concentration: 2.5 μg/mL.

    Western Blot: Approx 23-24 kDa band observed in Human Testis lysates (calculated MW of 22.6 kDa according to NP_003177.2 and NP_001001522.1). Preliminary testing also showed a band at approx 23 kDa in lysates of cell line HeLa and approx 25 kDa in Human Brea

    Peptide ELISA: antibody detection limit dilution 1:4000.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Minimize freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
  • Donati, Marseglia, Magi, Serratì, Cencetti, Bernacchioni, Nannetti, Benelli, Brunelli, Torricelli, Cossu, Bruni: "Sphingosine 1-phosphate induces differentiation of mesoangioblasts towards smooth muscle. A role for GATA6." in: PLoS ONE, Vol. 6, Issue 5, pp. e20389, (2011) (PubMed).

    Cencetti, Bernacchioni, Nincheri, Donati, Bruni: "Transforming growth factor-beta1 induces transdifferentiation of myoblasts into myofibroblasts via up-regulation of sphingosine kinase-1/S1P3 axis." in: Molecular biology of the cell, Vol. 21, Issue 6, pp. 1111-24, (2010) (PubMed).

    Nincheri, Luciani, Squecco, Donati, Bernacchioni, Borgognoni, Luciani, Benvenuti, Francini, Bruni: "Sphingosine 1-phosphate induces differentiation of adipose tissue-derived mesenchymal stem cells towards smooth muscle cells." in: Cellular and molecular life sciences : CMLS, Vol. 66, Issue 10, pp. 1741-54, (2009) (PubMed).

    Donoghue, Doran, Wynne, Pedersen, Dunn, Ohlendieck: "Proteomic profiling of chronic low-frequency stimulated fast muscle." in: Proteomics, Vol. 7, Issue 18, pp. 3417-30, (2007) (PubMed).

  • 抗原

    Transgelin (TAGLN)

    别名

    TAGLN

    背景

    TAGLN, SM22, SMCC, WS3-10, transgelin, SM22-alpha, DKFZp686P11128, TAGLN1, DKFZp686B01212, transgelin variant 2

    基因ID

    6876, 21345, 25123

    NCBI登录号

    NP_003177
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