Transgelin 抗体 (C-Term)
Quick Overview for Transgelin 抗体 (C-Term) (ABIN185188)
抗原
See all Transgelin (TAGLN) 抗体适用
宿主
克隆类型
标记
应用范围
质量等级
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抗原表位
- C-Term
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原理
- SM22 Alpha / Transgelin
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序列
- MTGYGRPRQI IS
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特异性
- NP_003177.2 and NP_001001522.1 represent identical protein. The transgelin protein is found in fibroblasts and smooth muscle and is known as a transformation or shape change protein that is involved with actin cross-linking. Transgelin is one of the earli
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交叉反应
- Cow, 犬, 人, 小鼠, 大鼠
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纯化方法
- Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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免疫原
- C-MTGYGRPRQIIS
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亚型
- IgG
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应用备注
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Immunohistochemistry: Paraffin embedded Human Prostate. Recommended concentration: 2.5 μg/mL.
Western Blot: Approx 23-24 kDa band observed in Human Testis lysates (calculated MW of 22.6 kDa according to NP_003177.2 and NP_001001522.1). Preliminary testing also showed a band at approx 23 kDa in lysates of cell line HeLa and approx 25 kDa in Human Brea
Peptide ELISA: antibody detection limit dilution 1:4000.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Minimize freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.
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Sphingosine 1-phosphate induces differentiation of mesoangioblasts towards smooth muscle. A role for GATA6." in: PLoS ONE, Vol. 6, Issue 5, pp. e20389, (2011) (PubMed).
: "Transforming growth factor-beta1 induces transdifferentiation of myoblasts into myofibroblasts via up-regulation of sphingosine kinase-1/S1P3 axis." in: Molecular biology of the cell, Vol. 21, Issue 6, pp. 1111-24, (2010) (PubMed).
: "Sphingosine 1-phosphate induces differentiation of adipose tissue-derived mesenchymal stem cells towards smooth muscle cells." in: Cellular and molecular life sciences : CMLS, Vol. 66, Issue 10, pp. 1741-54, (2009) (PubMed).
: "Proteomic profiling of chronic low-frequency stimulated fast muscle." in: Proteomics, Vol. 7, Issue 18, pp. 3417-30, (2007) (PubMed).
: "
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Sphingosine 1-phosphate induces differentiation of mesoangioblasts towards smooth muscle. A role for GATA6." in: PLoS ONE, Vol. 6, Issue 5, pp. e20389, (2011) (PubMed).
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- Transgelin (TAGLN)
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别名
- TAGLN
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背景
- TAGLN, SM22, SMCC, WS3-10, transgelin, SM22-alpha, DKFZp686P11128, TAGLN1, DKFZp686B01212, transgelin variant 2
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基因ID
- 6876, 21345, 25123
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NCBI登录号
- NP_003177
抗原
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