This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton.This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis.Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16.The Smith-Magenis syndrome region is the site of two related pseudogenes.